Chapter 18 - Biopsychology of Psychiatric Disorders Flashcards
Psychiatric disorders
A disorder of psychological function sufficiently severe to require treatment by a psychiatrist or clinical psychologist
DSM-5
The fifth and current edition of the Diagnostic and Statistical Manual of Mental Disorders; produced by the American Psychiatric Association
Reserpine
The first monoamine antagonist to be used in the treatment of schizophrenia; the active ingredient of the snakeroot plant
Haloperidol
A butyrophenone used as an antipsychotic drug
Phenothiazines
A class of antipsychotic drugs that bind effectively to both D1 and D2 receptors
Butyrophenones
A class of antipsychotic drugs that bind primarily to D2 receptors
Typical antipsychotics
The first generation of antipsychotic drugs
Atypical antipsychotics
Drugs that are effective against schizophrenia but yet do not bind strongly to D2 receptors. Also known as second-generation antipsychotics.
Clozapine
An atypical antipsychotic that is used to treat schizophrenia, does not produce Parkinsonian side effects, and has only a slight affinity for D2 receptors
Psychedelic drugs
Drugs whose primary action is to alter perception, emotion, and cognition
Lysergic acid diethylamide (LSD)
Hallucinogenic drug that alters perception, emotion, and cognition
Anhedonia
A general inability to experience pleasure
Clinical depression (major depressive disorder)
Depression that is so severe that it is difficult for the patient to meet the essential requirements of daily life
Reactive depression
Depression that is triggered by a negative experience
Endogenous depression
Depression that occurs with no apparent cause
Comorbid
The tendency for two or more health conditions to occur together in the same individual
Seasonal affective disorder (SAD)
Type of major depressive disorder in which episodes of depression typically recur during particular seasons—usually during the winter months
Peripartum depression
The intense, sustained depression experienced by some females during pregnancy, after they give birth, or both
Iproniazid
The first antidepressant drug; a monoamine oxidase inhibitor
MAO inhibitors
Antidepressant drugs that increase the level of monoamine neurotransmitters by inhibiting the action of the enzyme monoamine oxidase
Cheese effect
The surges in blood pressure that occur when individuals taking MAO inhibitors consume tyramine-rich foods, such as cheese
Tricyclic antidepressants
Drugs with an antidepressant action and a three-ring molecular structure
Imipramine
The first tricyclic antidepressant drug
Positive symptoms
Symptoms of schizophrenia that seem to represent an excess of typical function
Negative symptoms
Symptoms of schizophrenia that seem to represent a reduction or loss of typical function