Chapter 8 Flashcards
First law of Thermodynamics
Energy is neither created or destroyed
Second Law of Thermodynamics
Heat always moves from hotter objects to colder objects. “cold” is not energy and therefore cannot move
When energy is converted from one form to another, some of that energy becomes unavailable to do work, no energy transformation is 100%
Potential energy
Energy of an object based on its position
Kinetic energy
Energy of an object in motion
endergonic
delta G is positive, reaction requires energy
exergonic
delta G is negative, reaction releases energy
Free energy
useful energy, associated with a reaction, that can perform work
entropy
measure of the disorder in a system
metabolism
Sum total of all chemical reactions in an organism
anabolism
Complex molecules are made from simple molecules; energy input is required
catabolism
a pathway that breaks down molecules into smaller subunits, energy is released
metabolic pathway
The organization of all chemical reactions in a cell
catalyst
-speed up the rate of reactions
-is not altered by the reactions
-most are enzymes
-RNA can also be a catalyst (ribosomes)
energy of activation
amount of energy required to initiate a chemical reaction
enzyme
-Biological catalyst
-lower the energy barrier for reactions
Competitive inhibitor
Compete with the natural substrates for binding sites
non-competitive inhibitor
Bind to the enzyme at a different site (not the active site)
reversible inhibitor
Inhibitor bonds non-covalently to the active site and prevents substrate from binding.
non-reversible inhibitor
Inhibitor covalently bonds to side chains in the active site-permanently inactivates the enzyme
allosteric regulation
natural, noncompetitive, reversible inhibitors and/or activators of enzyme activity
active site
where substrate molecules bind to the active site of the enzyme
transition state
activation energy changes the reactants into unstable forms with higher free energy (transition state intermediates)