Chapter 75: Primary Wound Closure Flashcards

1
Q

What are the 3 divisions of the vascular supply to the skin?

A

Superficial/Subpapillary plexus
Middle/Cutaneous plexus
Deep/subdermal/subcutaneous plexus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the main differences between the cutaneous angiosomes in dogs and cats?

A

Dogs have a greater density of collateral SQ vessels
Cats have a smaller number and wider distribution of cutaneous perforating vessels

These differences apply mainly to the trunk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define the following:
Primary wound closure (First intention healing)
Delayed primary wound closure
Secondary Closure (Third intention healing)
Second intention healing

A

Primary wound closure = Sutured wounds
Delayed primary wound closure = suturing 2-5 days after initial injury, before granulation tissue development
Secondary Closure = Closure of the would after granulation tissue has formed in the wound bed
Second intention healing = Allow to heal without suturing - usually via contraction and epithelialization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the rate of epithelialization in primary wound healing?

A

1mm/day.

A perfectly apposed wound can therefore be epithelialized within 24-48hr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the reported % strength of wounded skin in comparison to normal skin at the following time points:
14 days
3-4 weeks
Several months

A

14 days - 5-10% strength
3-4 weeks - 25%
Several months/1 year - 70 - 80% strength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How does tension affect wound healing?

A

Tension can disrupt cutaneous perfusion and retard wound healing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are 5 things that can affect wound healing?

A

Tension
Pressure
Motion
Self-Mutilation
Patient Health

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What patient health factors can significantly retard epithelialization?

A
  • Uremia
  • Steroid excess (Cushing’s or drugs) Steroids prolong the inflammatory phase and delay cutaneous wound healing
  • Geriatric age (Decreased cutaneous perfusion, increased skin fragility, increases risk of infection)
  • Malnutrition
    -Methionine, cysteine and arginine all important
    -Fatty acids (within cell membranes, vital for cell function)
    -Vitamin C (collagen synthesis, cell mitosis and monocyte migration)
    -Zinc and iron (enzymatic reactions)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the reported benefits of using a scalpel for a skin incision over electrocautery/CO2 laser/radiowaves?

A

Scalpel incisions have approximately twice the wound strength at 10-12 days post-op compared to electrocautery
* Produce less drainage with faster and stronger healing
* Char will penetrate the skin with other methods

In humans, studies have concluded that incision made with electrocautery were faster and resulted in less post-op pain with no difference in scar formation of post-op infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is meant by the ‘golden period’ for wound management?

A

The golden period is a period of 3-6hr during which the bacteria within a minimally contaminated wound can multiply to 10^5 CFU per gram of tissue or per mL of exudate, at which point the risk of infection increases dramatically.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

List some differences between dogs and cats in regards to wound healing:

A

Generally speaking - cats heal weaker and you should leave their sutures in a little longer.
* Cats have lower cutaneous perfusion for the first week (by 2 weeks, no difference)
* Cats have a significantly lower wound breaking strength 1 week post-op
* Open wounds in cat heal largely by contraction whereas dogs heal largely by central “pull” of fibroblasts and epithelialization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Defects should generally be created and closed parallel to tension lines except for…

A

On distal limbs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How long may it take for the degree of trauma to be fully established after a crushing injury?

A

3-7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is a chain stitch knot?

What are its advantages?

A

An aberdeen knot!

Greater relative knot security and less volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the recommended suture tag length of buried knots?

A

3-5 mm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Which suture materials require 3-6 square knots for security (as apposed to 4-6)?

A

Polyglactin 910 (Vicryl)
Polyglytone (Caprosyn)
Nylon
Prolene

For size 3-0

17
Q

How many throws are required when tying to a loop at the end of a continuous pattern?

A

At least 5

18
Q

What are 2 options for continuous pattern closure of the SQ?

A

Simple continuous (bites perpendicular to incision)
Running horizontal mattress (Bites parallel to incision)

19
Q

What is recommended for ideal dermal apposition with a continuous horizontal intradermal pattern?

A

Length of each bite no more than 0.5cm
Alternating bites should be backtracked 1-2mm

20
Q

What are 2 advantages of the continuous vertical intradermal pattern?

A

Vascular supply to the wound edges is unlikely to be compromised as the suture material within the wound runs parallel to the cutaneous perforating vessels
Surgery time may be decreased

21
Q

What are the (5) techniques for correcting dog ears?

A

A: Removal of 2 small triangles
B: removal of one large triangle
C: Extension of fusiform incision
D: Removal of arrowhead
E: Half-Z correction

22
Q

What are two methods for correcting dog ears which are 2cm or smaller?

A

Apex cutaneous suture
Horizontal oblique dermal suture

A-choo!

23
Q

What are (6) methods of prevention/correction of dog ear formation in elliptical incisions?

A

A - Fudging - placing sutures further apart on longer side when discrepancy is small
B - Rule of halves
C - Sutures from ends to center with dog ear removal
D - Suturing from one end to the other with dog ear removal
E - Suturing from center to ends with dog ear removal
F - Lengthening the short side with half of a fusiform

24
Q

How may NSAIDs theoretically inhibit wound healing?

A

COX-2 production occurs at wound edges leading to infiltration of inflammatory cells and fibroblast proliferation within the first week

  • NSAIDs could theoretically inhibit this process via inhibition of COX-2
25
Q

What are (6) purported effects of therapeutic lasers?

A

Enhanced leucocyte infiltration
Increasing growth factors
Increasing macrophage activity
Increasing neovascularization
Increasing fibroblast and keratinocyte proliferation
Promoting early epithelialization

26
Q

How does a therapeutic laser work?

A

Photochemical effect said to enhance mitochondrial respiration and ATP synthesis

27
Q

What are 4 methods to correct a step defect?

A

A: Manipulation of suture knot
B: Placement of suture at same depth on each side of wound
C: Half-buried horizontal mattress with intradermal portion on low side
D. Place a stiff, untied suture (?) from superficial on high side to deep on the low

28
Q

How strong is a wound at 3-4 weeks?

A

25% of normal

29
Q

How strong is a wound at 10-14 days?

A

5-10% of normal

30
Q

Hair follicles are present where?

A

In the dermis and upper parts of the hypodermis at varying lengths.

31
Q

What are the layers of skin?

A

2 layers
Epidermis
Dermis

Hypodermis (SQ) below

32
Q

What are the three plexi of the skin?

A
  1. SQ or subdermal plexus
  2. cutaneous plexus
  3. Subpapillary plexus (small capillaries to epidermis)
33
Q

What is one reason dogs heal skin wounds better than cats?

A

Dogs have a greater density of collateral SQ vessels