Chapter 6: Phospholipid Bilayers Flashcards
The _____ nature of phospholipids drives the organization of phospholipid bilayer
amphipathic
Polar, hydrophilic _____ interact with water, while the nonpolar, hydrophobic _____ interact with each other and away from water
heads, tails
In water, lipids spontaneously form micelles (fatty acids, fats, sterols), bilayers, or liposomes (phospholipids) mostly via _____ interactions
hydrophobic
What is the Fluid-Mosaic Model?
the phospholipid bilayer of membranes is studded with membrane-spanning proteins
What are peripheral membrane proteins?
associated with the membrane but does not pass through it
What are integral membrane proteins?
passes through the phospholipid bilayer; aka transmembrane protein
Phospholipid bilayers are _____ _____ to different substances
selectively permeable
The _____ of phospholipid bilayers is affected by the _____ of phospholipid bilayers
permeability, fluidity
Unsaturations/double bonds: create _____ in the fatty acid tails, which _____ the packing between phospholipids; _____ Fluidity and Bilayer _____
kinks, decreases, increase, permeability
Increasing Fatty Acid Tail Length: more extensive _____ interactions that pack phospholipids together; _____ Fluidity and Bilayer permeability
hydrophobic, decrease
Increasing temperature: increases _____; _____ fluidity and bilayer permeability
energy, increase
_____ Fluidity = _____ Permeability
Increased, Increased
( therefore decreased, decreased)
adding _____ molecules to artificial membranes dramatically _____ their permeability
cholesterol, reduces