Chapter 3: What Do Proteins Look Like? Flashcards
primary structure
the unique sequence of amino acids in a protein
the order of the R-groups present in a polypeptide with affect that molecule’s ______ and ______
properties, function
primary structure is fundamental to its ______
function
Primary structure is also fundamental to the higher levels of _______ _______
protein structure
secondary structure is characterized by the _______ ______ that occurs between amino acids
hydrogen bonding
hydrogen bonding between sections of the same backbone is possible only when a polypeptide ______
bends
alpha helix
polypeptide’s backbone is coiled
beta pleated sheet
segments of a peptide chain bend 180° and then fold in the same plane
Each of the hydrogen bonds in an α-helix or a β-pleated sheet is _____relative to a covalent bond, but a large number of hydrogen bonds in these secondary structures makes them _____ _____. As a result, they increase the _____ of the molecule as a whole and help define its _____.
weak, highly stable, stability, shape
tertiary structure is a protein’s overall _____-_____ _____ that results from interactions between _____ that are brought together as the backbone bends and folds in space
three-dimensional shape, residues
tertiary structure depends on both _____ and _____ structures.
primary, secondary
quaternary structure is the combination of _____, referred to as subunits
polypeptides
macromolecular machines are cells that have complexes of ______ _____ that assemble to carry out a particular _____ (ex: the ribosome)
multiple proteins, function
they key thing to note is that protein structure is _____
hierarchical