Chapter 3: Amino Acids and Their Polymerization Flashcards
Macromolecules
large molecules important for life
Polymers
made from identical or similar building blocks strung together
Monomers
building blocks of polymers; arranging monomers in different order provides diversity across macromolecules
Dehydration Reactions
monomers link together to form polymers
Hydrolysis
polymers break apart with water
Enzymes
specialized proteins that mediate chemical reactions, such as dehydration reactions
Protein _____ is related to protein ______
function, structure
the many shapes and sizes of proteins reflect their amino acid _____ and _____.
compositions, sequence
one polymeric macromolecular family is a ______
protein
proteins are polymers whose monomeric subunits are _______
amino acids
amino acids ____ in ______ environments
ionize, aqueous
amino acids are defined by their ____ _____
side chains
What are the three general types of side chains?
- Charged- acidic (-) or basic (+); hydrophilic
- Polar but not charged; hydrophilic
- Nonpolar- usually a hydrocarbon; hydrophobic
Nonpolar side chains
contain mostly C and H, which have roughly equal electonegativities. Electrons are evenly shared in bonds
Polar (but not charged) side chains
contain a highly electronegative oxygen atom with a partial negative charge, making them polar
Polypeptide
a chain of amino acids (protein)
What gives proteins wide diversity?
there are only a set number of types of amino acids, but when a protein contains hundreds of amino acids, there are endless combinations
Amino acid sequences are described from the _____ terminus to _____ terminus.
amino, carboxy
Oligopeptides
chains with less than 50 amino acids
Polypeptides
chains with more than 50 amino acids
Residues
the conventional name for amino acids within a protein
protein folding is _____ favorable and largely ______
energetically, autonomous
amino acids polymerize when a bond forms between the ______ group of one amino acid and the ______ group of another
carboxyl, amino
Peptide Bond
covalently link amino acids together into chains