Chapter 6 (pdf15) Flashcards
The transition step of glycolysis links it to
TCA cycle
in the transition step, CO2 is removed through…
decarboxylation
in the transition step NAD+ is reduced to…
NADH
- each______ enters the transition step
- –reaction occurs TWICE for one glucose
pyruvate
yield from transition step includes
- reducing power NADH
- precursor metabolites
- —Acetyl CoA
completes the oxidation of glucose
TCA cycle
incorporates acetyl CoA from transition step*
-releases CO2 in net reaction*
TCA cycle
cycle turns ONCE for each acetyl CoA
-TWO turns for each glucose molecule
TCA cycle
the TCA cycle produces
- 2 ATP
- 6 NADH
- 2 FADH2
- 2 precursor metabolites
Nocardia loves the TCA cycle because
- complete oxidation of glucose ( big bang for buck)
- critical intermediates* for amino acids and lips (transition step)
- More reduced equivalents for respiration
why dont other species care as much about the TCA cycle?
They have Fermentation.
Use this pathway for making proteins not for
maximum reducing equivalents
each glucose consumed- glycolysis
2 NADH
each glucose consumed- TCA cycle
2FADH2 + 6NADH
recycles NADH and FADH2 and couples to synthesis of ATP
respiration
in respiration, oxidative phosphorylation has two parts…
- electron transport chain
- generated proton motive force (and NADH+ and FAD) - ATP synthase
- use proton gradient from (PMF) to synthesize ATP
group of membrane-embedded electron carriers*
-transfer of electrons produces a proton motive force
Electron transport chain in respiration
transfer of electrons in respiration produces
proton motive forces
four types of electron carriers
- Flavoproteins
- Iron-sulfur proteins
- Quinones
- Cytochromes
respiration is either
aerobic or anaerobic
in_____ respiration some prokaryotes have simplified ETC compared to eukaryotes
aerobic
mechanism of proton motive force
-certain carriers accept BOTH protons and electrons, some only accept electrons
respiration
pump protons across membrane proton gradient
proton motive force
first proposed the chemiosmotic theory and won nobel prize
Peter Mitchell
Harvest energy from proton motive force to synthesize ATP
ATP synthase
permits protons to flow back into the cell
ATP synthase
produces enough energy to phosphorylate ADP—->ATP
- 1 ATP is formed from entry of 3 protons
ATP synthase
-CO2 is removed through decarboxylation
transition step
-Remaining 2-C acetyl group joined to coenzyme A to form Acetyl CoA
transition step
-NAD+ is reduced to NADH
transition step
Modifies 3-C pyruvate from glycolysis to 2-C acetyl CoA
transition step