Chapter 6

Question 1

enzymes compared to catalysts (4)

Answer 1

-faster, need milder conditions, greater specificity, more regulated

Question 2

enzyme rates can approach what

Answer 2

the limit of the rate of diffusion of two molecules

Question 3

circe effect

Answer 3

allows some enzymes to catalyze reaction faster than predicted

Question 4

activation energy

Answer 4

delta G between two points determines rate at which equilibrium is reached

Question 5

enzymes do what and don’t do what

Answer 5

do increase the rates of reaction

don’t affect the equillibrium

Question 6

binding of reactants in enzyme active sites

Answer 6

provides substrate specificity and catalytic power

Question 7

show the overlap between substrate binding and transition state stabilization in a reaction

Answer 7

E+SESETSE+P
substrate binding: E+SES
Transition state stabilization:
ESETS

Question 8

enzymes gather and position substrates which in turn

Answer 8

makes the formation of transition state more frequent and lower the energy of activation

Question 9

transition state analogs

Answer 9

stable compounds whose structures resemble unstable transition states