Chapter 3

Question 1

Proline is a what instead of a what and is usually in combination with what

Answer 1

imino rather than an amino acid and in combination with glycine

Question 2

Methionine is one of two amino acids with a

Answer 2

sulfur group within its side chain

Question 3

Tyrosine can undergo what modification through what

Answer 3

post translation modification through phosphorylation

Question 4

what is post-translational

Answer 4

the amino acids are modified after they have been incorporated into the protein

Question 5

post translational modifications are reversible meaning

Answer 5

the phosphoryl group can be removed by phosphatases

Question 6

Serine and Threonine can undergo what

Answer 6

kinase-mediated phosorylation of their hydroxyl groups

Question 7

Two cysteine residues can form a what that is important for what

Answer 7

covalent linkage called a disulfide bond that is important for protein stabilization

Question 8

Disulfide bonds form through

Answer 8

the oxidation of the sulfhydryl groups of two cysteines to form a covalent linkage

Question 9

Lys and Arg always carry a

Answer 9

+1 net charge at physiological pH

Question 10

Histidine’s imidazole has a

Answer 10

pKa near physiological pH such that a fraction of cellular histidines will be +1 and the rest will carry a 0 charge