Chapter 5 Flashcards

1
Q

homotropic

A

when the normal ligand and modulator are the same

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2
Q

heterotropic

A

when the modulator is different from the normal ligand

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3
Q

allosteric proteins have what(R-state) and what(T-state)

A

active and inactive

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4
Q

what stabalizes the R state and what stabilizes the T state

A

allosteric activators and allosteric inhibitors

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5
Q

the binding and release of O2 from Hem

A

are allosterically regulated

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6
Q

binding the first O2 to hem causes

A

conformational changes making easier to bind more O2

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7
Q

O2 binding promotes and stabalizes

A

the R state which has higher O2 affinity than the T state

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8
Q

With T state hemoglobin the iron atom

A

is just outside the plane of the heme ring

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9
Q

with the pressures of oxygen found in the lungs:

A

Hb will completely saturate with O2

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10
Q

with the pressures of O2 found in the extremes of the body:

A

Hb will release approximately half of its O2

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11
Q

P50 of hb matches

A

the pressures of O2 found in periphery

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