Chapter 4 Flashcards
collagen us formed by
post translational modification
reactions to from collagen in the absence of vitamin C
cannot form stabilized bonds and it can cause scurvy
silk primary structure
amino acid repeat GSGAGA
silk’s structure in three dimensions
1) fully extended polypetide chains for strength
2) strands by hydrogen bonding for flexible
3) sheets by van der Waals and hydrophobic interactions flexible
intrinsically unstructured proteins
do not have a discrete three-dimensional structure, but has versatile characteristics that means one protein can assume different structures creating different biochemical functions
metamorphic proteins
structures of approximately equal energy that are in equilibrium
3 things about disulfide bridges
- forms between two cysteine residues
- can exist between two amino acid residues on the same chain
- have a stabilizing effect on proteins
which structure has myglobin and hemoglobin
-tertiary and then quaternary
the major force controlling tertiary protein structure
hydrophobic effect
5 steps of folding a globular protein
- formation of secondary structure
- formation of foains through aggregation
- molten globule formation
- adjustments in the conformation of domains
- final protein monomer formation