Chapter 4 Flashcards
energy for protein denaturation is
small, and equivalent to a few hydrogen bonds
primary structure-there is a repeating structural pattern of
NCCNCC
secondary-regularities by the main chain bonds what
amide hydrogen and carbonyl oxygen groups
secondary-characterized by
a specific pattern of hydrogen bonding
examples of secondary are
alpha helicies and beta sheets
to represent a viable form of secondary structure, the folding pattern must
1) optimize the hydrogen bonding potential of the main chain groups
2) represent a favored conformation of the polypeptide chain
configuration
spatial arrangement of atoms around double bonds can only by changed by breaking bonds
conformation
spatial arragnement of groups that are free to assume different positions in space without breaking bonds
rotation around what bond is restricted due to what
C-N bond due to the partial double bond nature of the peptide bond
the six atoms of the peptide group are
planar-the oxygen of the carbonyl group and the hydrogen of the amide nitrogen are trans to each other