Chapter 5: Integumentary System Flashcards
What does the integumentary system consist of?
Skin
Hair
Nails
Sweat glands
Sebaceous glands
The two distinct regions of the integumentary system
Epidermis
Dermis
(Deep to skin) Hypodermis
superficial region that consists of epithelial tissue and is avascular
Epidermis
underlies epidermis. mostly fibrous connective tissue and is avascular
Dermis
not part of the skin but shares some functions
composed of adipose tissue that absorbs shock and insulates
anchors skin to underlying structures
Hypodermis
What does the epidermis mainly consist of?
keratinized stratified squamous epithelium
What are the 4 cell types found in epidermis?
- keratinocytes
- melanocytes
- dendritic (langerhans) cells
- tactile (merkel) cells
- keratinocytes
- melanocytes
- dendritic cells
- tactile cells
4 cell types found in the epidermis
- millions slough off everyday
- tightly connected by desmosomes
- major cells of the epidermis
- produces fibrous keratin (protein)
Keratinocytes
- produces pigment melanin, which is packaged into _____somes
- spider-shaped cells located in the deepest epidermis
Melanocytes
Melanosomes
________ are transferred into keratinocytes, where they protect nucleus from UV damage
Melanosomes
- start shaped macrophages that patrol deep epidermis
- key activators of the immune system
Dendritic (langerhans) cells
- sensory receptors that sense touch
Tactile (merkel) cells
- consists of a single row of stem cells that actively divide
- also known as stratum germination
- 10-25% composed of melanocytes
Stratum basale
- weblike system of intermediate prekeratin filaments attached to desmosomes (makes it appear spiky)
- allows resistant tension and pulling
- melanin granules + dendritic cells are most abundant in this layer
Stratum spinosum (prickly layer)
- 4-6 cell layers thick, cells are flattened
- cell appearance changes
- cells accumulate keratohyaline granules that help form keratin in the upper layer
- calls also accumulate lamellar granules, a water-resistant glycolipid that slows water loss
Stratum Granulosum
- found only in thick skin
- consists of a thin clear band of 2-3 rows of dead keratinocytes
- superficial to stratum granulosum
Stratum Lucidum (clear leayer)
- -20-30 layers of flat, anucleated keratinized dead cells
- accounts for ¾ of epidermal thickness
- dead cells have protective functions
Stratum Corneum (horny layer)
- strong, flexible connective tissue
- cells include fibroblasts, macrophages, and occasionally white blood cells
- fiber in the matrix binds the body hyde
Dermis
contains epidermal hair follicles, oil glands, and sweat glands
Dermis
The 2 layers of dermis
Papillary
Reticular
What kind of tissue is in the papillary layer?
Areolar connective tissue
- areolar connective tissue consisting of collagen fibers, elastic fibers, blood vessels
- loose fibers allow phagocytes to patrol for microorganisms
Papillary Dermis Layer
- consists of course, dense fibrous connective tissue
- collagen fibers provide strength and resiliency
- ECM contains pockets of adipose cells.
Reticular Dermis Layer
What kind of connective tissue is in the reticular dermis layer?
Corse, dense irregular connective tissue