Chapter 5: Epithelial Tissues Flashcards
This tissue is composed of flattened, irregularly shaped cells that form a continuous surface and supported by an underlying basement membrane
It’s found in lining surfaces in passive transport (diffusion) of either gases (as in the lungs) or fluids (as in the walls of blood capillaries); forms lining of the pleural, pericardial, and peritoneal cavities
Simple squamous epithelium
This tissue type consists of cells perpendicular to the basement membrane that appear square with a round nucleus usually located within the center of the cell
These tissue cells usually line small ducts and tubules that may have excretory, secretory, or absorptive functions (e.g., collecting tubules in kidney, small excretory ducts in salivary glands)
Simple cuboidal epithelium
This tissue consists of cells perpendicular to the basement membrane that appear columnar and tall with elongated nuclei that may be located towards the base, center, or occasionally apex of cytoplasm (nucleus polarity)
They are generally found on absorptive surfaces (i.e., stomach)
Simple columnar epithelium
This tissue type is found largely in the female reproductive tract and assists in the movement of fluid or minute particles
Simple columnar ciliated epithelium
The appearance of cells in this tissue conveys the wrong impression of more than one cell layer because each cell remains connected to the basement membrane
It is found almost exclusively in the airways of the respiratory system (often called respiratory epithelium)
Pseudostratified columnar ciliated epithelium
How can pseudostratified columnar ciliated epithelium be distinguished from stratified epithelium?
- Individual cells of pseudostratified epithelium demonstrate nucleus polarity
- Cilia are never present on true stratified epithelium
_____________________________ is defined as epithelium consisting of two or more layers with mainly protective function with the degree and nature of stratification related to physical stress exposure (generally ill-suited for absorption – thickness)
Stratified epithelium
This tissue consists of variable number of cell layers that exhibit maturation from a cuboidal basal layer to a flattened surface area
It’s adapted to withstand abrasion with plentiful cell junctions and intermediate filament (keratin) cytoskeleton (e.g., oral cavity, pharynx, esophagus, anal canal, uterine cervix, vagina)
Stratified squamous epithelium
This tissue constitutes epithelial surface of skin (epidermis) and is adapted to withstand constant abrasion and dessication
It’s marked by intermediate (keratin) filaments cross-linked with proteins in keratinization, resulting in a tough, non-living surface layer
Keratinizing stratified squamous epithelium
This tissue consists usually of only two to three layers of cuboidal cells
It’s often confined to lining of larger excretory ducts of exocrine glands
Stratified cuboidal epithelium
__________________ is found only in the urinary tracts of mammals, where specialized to withstand stretch and toxicity
Transitional epithelium
Intercellular junction type that controls paracellular diffusion and prevents exchange of intrinsic proteins and lipids between apical and basolateral plasma membrane
Tight junctions
What are the main protein components of tight junctions?
Claudins, occludins
What cytoskeleton connections do tight junctions make?
Actin microfilaments
Where are tight junctions found in epithelial cells?
At the luminal end of the lateral cell membrane
What are six characteristics of epithelial tissues?
- Function as an interface tissue
- Exhibit polarity
- Avascular but innervated
- Supported by connective tissue
- Regenerative
- “Cellular” (little extracellular space)
When you skin your knee, what tissue bleeds?
Connective tissue - remember epithelial tissue is avascular and cannot bleed
What’s the name of the uppermost portion of the basal membrane?
Basal lamina
The basement membrane is composed of two layers. What are they?
- Basal lamina
- Reticular lamina
What are the four structural/functional domains of an epithelial cell?
- Apical
- Lateral
- Basal
- Basolateral
The _______________ surface is also called the “free surface” and borders the lumen or exterior surface
Apical
__________________ refers to the side surface that faces neighboring cells
Lateral
The __________________ surface is the bottom surface near the basal lamina
Basal
The _________________ surface is a subset of lateral surface that resides within the basal and lateral domains and covers “corners”
Basolateral
What type of epithelium allows passage of materials by diffusion and filtration in sites where protection is not important and secretes lubricating substances in serosae
Simple squamous epithelium
What type of epithelium aids in secretion and aborption?
Simple cuboidal epithelium
What type of epithelium functions in absorption; secretion of mucus, enzymes, and other substances; and when ciliated movement of mucus or reproductive cells by ciliary action
Simple columnar epithelium
__________________ cells secrete mucus
Goblet
What type of epithelium functions in secretion, particularly of mucus, and propulsion of mucus by ciliary but is present only in a few places in the body?
Pseudostratified columnar epithelium
What type of epithelium protects underlying tissues subjected to abrasion?
Stratified squamous epithelium
Where would non-keratinized stratified squamous epithelium be found?
Moist linings of esophagus, mouth, vagina
Where would keratinzed stratified squamous epithelium be found in the body?
Epidermis of the skin, a dry membrane
______________________ is the process of cells filling with keratin
Cornification or keratinization
In ________________________ stratified squamous epithelium, apical cells have squamous shape that retain nuclei and are often found in areas exposed to abrasion.
Non-cornified or non-keratinized
In _______________________ stratified squamous epithelium, apical cells retain shape but lack nuclei; cells are “dead,” composed only of protein and lipid
Cornified or keratinized
_________________ __________________ epithelium functions in protection and lines the larger ducts of mammary glands, sweat glands, salivary glands, and the pancreas
Stratified cuboidal epithelium
What type of epithelium is found in the vas deferens and the pharynx?
Stratified columnar epithelium
What type of epithelium is a “true” stratified epithelium that can “stretch,” thereby found in the lining of the urinary bladder, ureters, and urethra?
Transitional epithelium