CHAPTER 5 Flashcards
active virus
capable of being replicated
inactive virus
unable to replicate
obligative intracellular parasites
understand that these require a host cell to replicate
capsid
the protein shell of a virus that encases the viral genome
virion
the complete virus particle, including the capsid and the envolved genetic material
enveloped virus
a virus that has an outer lipid membrane surrounding the capsid
viral genome
the genetic material of the virus
adsorption
the virus attaches to the host cell and adsorbs specifically to the receptor sites on the cell membrane
penetration and uncoating
the virus enters the host cell and its genetic material is released
synthesis
the host cell machinery replicates the viral genome and synthesizes viral proteins
assembly
new viral particles are assembled inside the host cell
release
new viruses are released from the host cell, often killing it in the process
order of viral replication
- Adsorption- virus attaching to host cell via receptor sites on the cell membrane
- penetration/uncoating- virus enters host cell, releases its genetic material inside
- synthesis- host cell machinery replicates viral genome/synthesizes viral proteins
- assembly- new viral particles are assembled inside the host cell
- release- new viruses release from the host cell, killed in the process
prion
type of infectious agent composed of only protein
prion composition
made of abnormal proteins that cause diseases
BSE or Bovine Spongiform Encephalopathy
a neurodegenerative disease in cattle, also known as “mad cow disease”
caused by prions
viroid
infectious agent composed of a short strand of circular, single stranded RNA