CHAPTER 12 Flashcards

1
Q

immune system

A

the body’s defense against infectious organisms and other harmful invaders

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2
Q

self vs nonself

A

the immune system distinguishes between the body’s own cells and foriegn cells

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3
Q

antigen

A

any molecule that can stiulate an immune response

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4
Q

PAMPs (pathogen associated molecular patterns)

A

structures found on pathogens

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5
Q

PRRs (Pattern recognition receptors)

A

found on immune cells that recognize PAMPs

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6
Q

lymphatic system

A

system of vessels and organs that helps protect and maintain the fluid environment of the body

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7
Q

bone marrow
thymus

A

bm- produces blood cells, including immune cells
th- location where T cells mature

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8
Q

physical and chemical defenses

A

the body’s first line of defense is the skin and mucous membranes
chemical defenses are enzymes and acids

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9
Q

physical barriers

A

skin and mucous membranes prevent pathogens from entering
skin- keratin
mucous- mucus traps mo

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10
Q

chemical defences

A

example like lysozyme (in tears) and stomach acid that destroy or inhibit pathogens

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11
Q

defensive mechanisms in respiratory tract

A

nasal hair, mucus, ciliated epithelium, sneezing and coughing help prevent pathogens from entering the lungs

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12
Q

microbiome role

A

microbiota can prevent pathogenic mo from colonizing

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12
Q

urinary and vaginal defenses

A

urination and vaginal secretions help flush out mo

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12
Q

how does mouth protect

A

saliva washes microbes into the stomach

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12
Q

how do eyes protect themselves

A

tears and eye lubricants contain lysozyme, an enzyme that breaks down bacterial cell walls
blinking removes debris and mo

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12
Q

how does vomiting and defecation protect

A

expels harmful subtances, pathogens and toxins from the digestive system

13
Q

sebaceous secretions

A

contain antimicrobial compounds that inhibit microbial growth on the skin

14
Q

sweat

A

contains salt and antimicrobial peptides that inhibit microbial growth

15
Q

lymph node

A

small bean shaped structure that filters lymph and contains lymphocytes

16
Q

why do lymph nodes swell

A

swelling occurs when lymphocytes proliferate in response to detecting a pathogen or inflammation
can be a sign of infection, immune response or rarely cancer

17
Q

blood composition

A

RBCs, WBCs, platelets
Plasma

18
Q

stem cells in the bone marrow differentiate into:

A

myeloid lineage: RBCs, platelets, granulocytes
lymphoid lineage: lymphocytes

19
Q

bone marrow transplants can

A

replace damaged stem cells, creating a new functional immune system

20
Q

leukocytes

A

WBCs
types: granulocytes and agranulocytes

21
Q

granulocytes

A

type of WBC containing granule in their cytoplasm

22
Q

granules

A

granules contain enzymes and antimicrobial substances that destroy pathogens, signal other immune cells, assist in inflammation

23
Q

cytokines

A

small signaling proteins released by immune cells

24
Q

T/F: PAMP is an antigen

A

FALSE

25
Q
A