Chapter 47: The Child with a Hematologic Alteration Flashcards
characterized by uncontrolled formation and deposition of fibrin thrombi
disseminated intravascular coagulation (DIC)
manifestations may include excessive bleeding from injury, petechiae, and blood oozing from minor procedure sites
disseminated intravascular coagulation (DIC)
treatment for iron deficiency anemia involves ___________
replacing iron
acute sequestration crisis can result in these two complications
acute anemia
respiratory failure
thalassemia major presents in children who inherit (1,2) copy/copies of the gene mutation
2
patients with moderate to severe hemophilia are at risk for bleeding in the _________
joints
treatment for painful episodes of a vasoocclusive crisis includes oral or IV __________ such as ___________ and/or _________, oral/IV ____________, aggressive ____________________ use, consistent pain ________________, and ______________ pain management
analgesics, morphine, NSAIDs, hydration, incentive spirometry, assessment, nonpharmacologic
thalassemia minor presents in children who inherit (1,2) copy/copies of the gene mutation
1
three causes of iron deficiency anemia in children
- decreased iron intake
- increased iron/blood loss
- periods of increased growth
complex process that results in simultaneous bleeding and clotting
disseminated intravascular coagulation (DIC)
treatment for thalassemia focuses on three main aspects
RBC transfusions, chelation therapy, splenectomy
most common form of anemia in children
iron deficiency anemia
this condition is caused by a genetic abnormality in hemoglobin synthesis, where there is a reduction or absence of one of the chains of normal hemoglobin
thalassemia
iron deficiency anemia has been linked to consumption of ___________, particularly before 12 months of age
cows’ milk
characterized by underproduction of a carrier protein for factor VIII
von Willebrand disease
another name for thalassemia major
Cooley anemia
two age groups that have the most rapid growth and therefore increase risk of iron deficiency anemia
infants, adolescents
diagnosis of thalassemia is made based on this lab work (4)
CBC, reticulocyte count, serum iron, TIBC
dactylitis (hand-and-foot syndrome) in vasoocclusive crisis occurs in children aged _________ to _________ and is characterized by ________________________
6 months, 4 years
swelling of hands or feet, pain, warmth in affected area
diagnosis of iron deficiency anemia involves these four lab tests
CBC, serum ferritin, serum iron, TIBC
this bleeding disorder can cause septic shock and multiorgan failure
disseminated intravascular coagulation (DIC)
hemophilia C lacks factor ____
XI
the dietary supplement ____________ helps blood cells form appropriately in patients with sickle cell disease
folic acid
treatment for acute chest syndrome with vasoocclusive crisis involves IV ___________ at ______ times maintenance, ___________, ___________, _____ transfusion, and ___________.
hydration, 1-1.5, antibiotics, oxygen, RBC, analgesics