Chapter 4 terms Flashcards

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1
Q

nucleic acid

A

polymers of nucleotides; polynucleotides

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2
Q

nucleotides

A

monomers of nucleic acids

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3
Q

DNA

A

deoxyribonucleic acid; deoxyribose

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4
Q

what is the main function of DNA

A

store and transmit biological information

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5
Q

what is the structure of DNA

A

double helix

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6
Q

how does the double helix strand work in DNA

A

2 strands; alternating sugar-phosphate backbone; hydrophobic interactions between bases

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7
Q

what bonds are associated with DNA

A

hydrogen

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8
Q

What are the base pairs for DNA

A

A,T,C,G

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9
Q

RNA

A

ribonucleic acid; ribose

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10
Q

what is the main function of RNA

A

protein synthesis

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11
Q

what is the structure of RNA

A

hairpin

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12
Q

how does the hairpin structure work in RNA

A

1 strand; unpaired region forms a loop while antiparallel base paring forms double helix

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13
Q

what are the nitrogenous bases of RNA

A

A,U,C,G

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14
Q

what are the nitrogenous bases

A

A,T,U,C,G

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15
Q

nucleoside

A

nucleotide without phosphate group

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16
Q

how are nucleotides bonded

A

by phosphodiester linkages

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17
Q

what are the nucleotide components

A
  1. phosphate group
  2. 5 carbon sugar
  3. nitrogenous base
18
Q

what bond hold together nitrogenous bases

A

hydrogen bonds

19
Q

semi conservative model

A

way DNA replicates; each strand of an existing DNA serves as a template for DNA replication

20
Q

transcription

A

translates DNA to RNA

21
Q

translation

A

RNA into protein

22
Q

mRNA

A

messenger RNA; controls protein synthesis

23
Q

tRNA

A

transfer RNA; carries a specific amino acid

24
Q

what are pyrimidines

A

U, T, and C

25
Q

what are purines

A

A and G

26
Q

what and who discovered x-ray crystallography

A

way to measure the distance between atoms in DNA; Rosalind Franklin and Maruice Wilkins

27
Q

why was Erwin Chargaff important

A

discovered that number of purines=number of pyrimidines

28
Q

what did James Watson and Francis Crick discover

A
  1. 2 strands held together by hydrogen bonds
  2. complementary base pairing
  3. double helix
  4. 3’prime-5’prime and 5’prime-3’prime (antiparallel)
29
Q

what makes up the double helix strcuture

A
  1. nitrogenous base pairs face interior
  2. sugar phosphate backbone faces exterior
30
Q

what does antiparallel mean in DNA

A

form the ladder sides rows of the DNA; how DNA structure is put together

31
Q

5’prime

A

phosphate group; direction; end of nucleic acid

32
Q

3’prime

A

hydroxyl group; new nucleotides are added to unlinked 3’

33
Q

template strand

A

strand of RNA or DNA used to make a new, complementary strand

34
Q

complementary strand

A

phosphodiester linkages form to create a new strand

35
Q

what are the two types of distance between helix twists

A
  1. major groove
  2. minor groove
36
Q

which groove is the largest distance between twists

A

major grove

37
Q

which groove has the smallest distance between twists

A

minor groove

38
Q

how does the flow of information work in a eukaryotic cell

A

DNA (nucleolus)—> mRNA (nucleolus and cytoplasm)—> protein synthesis (ribosome)—>polypeptides and amino acids

39
Q

what is DNA ligase

A

an enzyme that joins pieces of DNA by catalyzing the formation of phosphodiester linkage between pieces of DNA

40
Q

What is DNA polymerase

A

any type of enzyme that catalyzes synthesis of DNA