Chapter 4 Flashcards
Define Bacteriophage
Viruses that Infect bacteria
What is the unit used to measure the Bacteriophage?
Nanometer
What is the length range of the Bacteriophage?
24-200
What does the Bacteriophage consist of?
2 points
Head
Tail
What is the Bacteriophage’s head known as?
Capsid
What is the function of this head?
Protection
What does this head protects?
Nucleic acid
What is this nucleic acid?
DNA
Which nucleic acid is rarely found in the head?
RNA
Describe Bacteriophage’s Tail
Tube
Describe this tube
Hollow
Describe the occurrence of Bacteriophage’s Tail
Attached
What is the Bacteriophage’s Tail attached to?
Head
What does Bacteriophage’s Tail consist of?
3 points
Sheath
Base plate
Fibers
Describe this sheath
Contractile
Where is the contractile sheath in the tail?
Surrounds it
Where is the base plate and the fibers at ,in the tail?
Its end
Describe the occurrence of these fibers
Attached
What are the fibers attached to?
Base plate
What are the 3 steps of Bacteriophage when infecting host cells?
Adsorption
Attachment
Contraction/ Penetration
What is the adsorption mediated by?
Fibers
What is the function of these fibers?
Attachment
What do these fibers attach to?
Receptors
Describe these receptors
Specific
Where are these specific receptors found on?
Bacterial cell
What feature of the fibers is essential in a determination?
Type
What feature of a Bacteriophage does the type of fibers determine?
Specificity
What is this specificity for?
Host
What is the attachment of the Bacteriophage mediated by?
Base plate
Describe this attachment
Irreversible
What does the Bacteriophage attach to
Bacterium
What makes the contraction/penetration?
Sheath
What happens when the sheath contracts?
Injection
What is injected due to the contraction of the sheath?
Nucleic acid
What is this nucleic acid injected into?
Bacterial cell
Which 2 parts of the Bacteriophage are left empty outside?
Head
Tail
What are the 2 multiplication cycles of the Bacteriophage?
Lytic
Temperate
Describe the Bacteriophage in the lytic cycle
Virulent
What does this virulent Bacteriophage do firstly in the lytic cycle?
Multiply
Where does this virulent Bacteriophage multiply inside?
Bacteria
What does this virulent Bacteriophage then do with the bacterial cell?
Kills it
How does the Bacteriophage kill this bacterial cell?
Lysis
At which part of the lytic cycle does this Bacteriophage kill the bacterial cell by lysis?
End
What is the Temperate cycle also known as?
Lysogenic
What feature of the virus is involved in the Temperate cycle?
DNA
What happens to this DNA?
Integrates
What does this DNA integrate into?
Bacterial chromosome
What then happens to the DNA and the bacterial chromosome together?
Replicated
When does the replication of these DNA and the bacterial chromosome occur?
During cell division
What is not usually done by the temperate viruses?
Killing
What do the Temperate viruses not usually kill?
Bacterial cells
Describe these bacterial cells
Host
Which host bacterial cells are not usually killed by the Bacteriophage?
Which they infect
What are these infected bacteria known as in the Temperate cycle?
Lysogenic
What is the virus known as in this state?
Prophage
What does the lysogenic bacteria acquire?
Properties
Describe these properties
New
What feature of the Bacteriophage changes the properties of the bacterial cell?
Genes
Describe these genes
Extra
What is the process of changing the bacterial properties by acquiring new ones due to the Bacteriophage’s new genes known as?
Lysogenic/Phage conversion
Describe the significance of the lysogenic/phage conversion
Clinical
What is produced so that the lysogenic/phage conversion could be clinically significant?
Exotoxins
What is an example of a bacteria that produces these exotoxins?
Corynebacterium diphtheria
What is the Exotoxin production by Corynebacterium diphtheria mediated by?
Gene
What carries this gene?
Bacteriophage
What property is acquired by the lysogenic bacteria?
Immunity
What is the lysogenic bacteria immune to?
Infection
What causes this infection in which the bacteria is immune to?
Another virus
What is the fate of the Bacteriophage in the Temperate cycle? (2 points)
Propagate
Detach
Describe this propagation
Indefinite
What does the Bacteriophage propagate in?
Daughter cells
What does the Bacteriophage detach from in the Temperate cycle?
Chromosome
Describe this detachment (2 points)
Spontaneous
Or
Induced
What is this detachment induced by?
Several conditions
Describe the conditions which induce the detachment of Bacteriophage
Exposure
What are the 3 exposures which induce the detachment of Bacteriophage?
UV
Or
Radiation
Chemicals
Describe this radiation
Ionizing
Describe these chemicals
Mutagenic
What do Bacteriophages sometimes do while detaching?
Carry genes
What are these genes of?
Bacterial chromosome
What does the Bacteriophage carry the genes of bacterial chromosome to?
Another bacteria
What is the process of carrying the genes of bacterial chromosome by a Bacteriophage to another bacteria known as?
Specialized Transduction
What can be terminated in the fate of the Temperate cycle?
Lysogenic state
What is the Bacteriophage important in?
2 points
Typing
Cloning
What is typed by the Bacteriophage?
Bacteria
What is this bacteria typed with? (2 points)
Reactions
Antigens
Describe these reactions (2 points)
Identical
Biochemical
Describe these antigens
Common
When is the typing of bacteria by the Bacteriophage usually done?
Outbreak
For what is the typing of bacteria by the Bacteriophage usually done during an outbreak?
Identification
What is identified due to the typing of bacteria by the Bacteriophage during an outbreak?
Infection
What feature of infection is identified due to the typing of bacteria by the Bacteriophage during an outbreak?
Source
What is an example of these infections?
Wound
What is the bacteria that produces this wound infection?
Staphylococcus aureus
Describe the cloned Bacteriophage
Vector
What is this vector cloned in?
Techniques
Which techniques is the vector cloned in?
Recombinant