Chapter 317 - Principles and practice of chemotherapy

Question 1

What is the minimally clinically detectable tumour cell mass?
a) 10^5 cells
b) 10^6 cells
c) 10^8 cells
d) 10^9 cells

Answer 1

D - 10^9 cells

Question 2

Most cancer staging systems are based on primary tumour size, lymph node metastasis and which of the following?
a) Distant metastasis
b) Tumour grade
c) Sentinel lymph node mapping
d) Immunophenotyping

Answer 2

A- Distant metastasis

Question 3

Which of the following may impact carboplatin dosing?
a) Presence of hepatic neoplasia
b) Reduced glomerular filtration rate
c) Systemic hypertension
d) Presence of lower urinary tract signs

Answer 3

B - Reduced glomerular filtration rate

Question 4

Administration of antibiotics in the absence of signs of sepsis is warranted post chemotherapy when a neutrophil count under what cut off is documented?
a) <1200/mcL
b) <1000/mcL
c) <750/mcL
d) <500/mcL

Answer 4

C - <750/mcL

Question 5

Excreta should be treated as hazardous for how many days after administration of injectable chemotherapy?
a) 3 days
b) 5 days
c) 7 days
d) 21 days

Answer 5

A - 3 days

Question 6

The level and prevalence of expression of what can increase with exposure of certain cancer cells to chemotherapy?
a) Cyclic AMP
b) Transmembrane P-glycoprotein
c) C-Kit
d) P53

Answer 6

B - Transmembrane P-glycoprotein