Chapter 200 - Coronavirus Flashcards
Approximately what percentage of feline coronavirus infections (FCoV) will result in feline infectious peritonitis (FIP)?
a. 5%
b. 10%
c. 20%
d. 25%
a. 5%
For up to how long can cats shed coronavirus within their faeces after infection?
a. 6 months
b. 8 months
c. 18 months
d. 24 months
d. 24 months
A cat is infected with FIPV and mounts a predominantly TH1 immune response. Based on this cat’s immune response, what is the most likely disease outcome?
a. Resistance to FIP
b. Development of non-effusive FIP
c. Development of effusive FIP
d. Subclinical infection and recrudescence at a later date
a. Resistance to FIP
In cases of neurological FIP, which part of the brain are lesions typically centred around?
a. Cerebellum
b. Hypothalamus
c. Olfactory bulb
d. Ventricles
d. Ventricles
Mutation in what open reading frame (ORF) is considered essential for replication of feline enteric coronavirus within monocytes and macrophages?
a. ORF2
b. ORF3
c. ORF6
d. ORF7
d. ORF7
What percentage of cats with confirmed FIP are serology negative?
a. 2%
b. 7%
c. 10%
d. 12%
Bonus question: why are they serology negative?
c. 10%
due to formation of antigen-antibody complexes, results in false negative results
What does IHC of lesions of cats with FIP demonstrate?
a. Granulomatous lesions containing FCoV antigen
b. Neutrophilic inflammation with intracellular bacteria
c. Eosinophilic inflammation containing FCoV antigen
d. Lymphocytic inflammation
a. Granulomatous lesions containing FCoV antigen
What is the mechanism of action of GS-441524?
a. Cysteine protease inhibitor
b. Nucleoside analog
c. Immunomodulator
d. Integrase inhibitor
b. Nucleoside analog
In canine coronavirus infection (CCoV) where does the virus replicate?
a. Villi crypts
b. Lymph nodes
c. Villi sides and tips
d. Respiratory epithelium
c. Villi sides and tips
