Chapter 204 - Canine distemper

Question 1

What genus does the Canine Distemper virus (CDV) belong to?
a) Lyssavirus
b) Morbillivirus
c) Ephemerovirus
d) Novirhabdovirus

Answer 1

B

Question 2

Which virus that affects humans belongs to the same genus as Distemper?
a) Rubella
b) Ebolavirus
c) Measles
d) Shingles

Answer 2

C

Question 3

Which cell types does CDV initially infect and destroy?
a) Glial cells and astrocytes
b) Respiratory epithelial cells
c) Lymphocytes and mononuclear cells
d) Enterocytes

Answer 3

C

Question 4

Following initial infection with CDV, what receptor allows binding of the virus to affect neuronal cells?
a) Transferrin
b) Aminopeptidase N
c) Nectin-4
d) P75 neurotrophin

Answer 4

C
a = parvo/panleukopenia, b = feline coronavirus receptor site (FIPV II), d = facilitate rabies entry (but multifactorial)

Question 5

Up to what period of time can CDV remain viable in the environment to facilitate indirect transmission?
a) A few hours
b) A few days
c) 5-7 days
d) 10-14 days

Answer 5

B - labile virus, easily inactivated by disinfectants

Question 6

Which antemortem source tends to yield the least amount of CDV using RT-PCR techniques?
a) Conjunctival swabs
b) Deep pharyngeal swabs
c) Nasal swabs
d) Rectal mucosal swabs

Answer 6

A