Chapter 209 - Blastomycosis and histoplasmosis Flashcards
What is the most common route of infection for blastomycosis?
a. Respiratory route
b. Faecal-oral route
c. Vector-borne
d. Direct contact with mucosal surfaces
A - Respiratory route
Which biochemical abnormality is most commonly seen in blastomycosis?
a. Azotaemia
b. Panhypoproteinaemia
c. Hypercalcaemia
d. Hyperbilirubinaemia
c. Hypercalcaemia
What is the most common finding on thoracic radiography in blastomycosis?
a. Pleural effusion
b. Pnemothorax and pneumomediastinum
c. Alveolar pattern
d. Interstitial pattern
d. Interstitial pattern
What percentage of dogs with blastomycosis test positive on serology?
a. 85%
b. 65%
c. 50%
d. 25%
c. 50%
What is the treatment of choice for blastomycosis in dogs with evidence of CNS involvement?
a. Itraconazole
b. Amphotericin B
c. Fluconazole
d. Ketoconazole
b. Amphotericin B
What age group is most commonly affected in feline histoplasmosis?
a. 12-18 months
b. <4 months
c. 2-4 years
d. 7+ years
b. <4 months
What is considered the treatment of choice in feline histoplasmosis?
a. Itraconazole
b. Amphotericin B
c. Fluconazole
d. Ketoconazole
a. Itraconazole
What is the usual appearance of histoplasmosis organisms on cytology of affected tissue?
a. Pyogranulomatous inflammation, numerous small round to oval intracellular yeast cells characterised by a basophilic centre and a light halo
b. Pyogranulomatous or suppurative inflammation, often with thick walled yeasts that bud to form daughter cells from a broad base
c. Eosinophilic inflammation with broad, thin walled and occasionally septate hyphae
d. Circular dense organisms surrounded by large capsules, with minimal inflammatory response
a. Pyogranulomatous inflammation, numerous small round to oval intracellular yeast cells characterised by a basophilic centre and a light halo
What is the most common haematological abnormality seen in dogs and cats with histoplasmosis?
a. Eosinophilia
b. Pancytopaenia
c. Normocytic normochromic anaemia
d. Lymphocytosis
c. Normocytic normochromic anaemia
Which form of histoplasmosis has the best prognosis?
a. GI disease
b. Cutaneous signs
c. Pulmonary signs
d. Ocular signs
c. Pulmonary signs