Chapter 25-26 Flashcards
What hormones are secreted from the anterior pituitary?
growth hormone, thyroid-stimulating hormone, adrenocorticotropic hormone, follicle-stimulating hormone, luteinizing hormone
What hormones are secreted from the posterior pituitary?
vasopressin and oxytocin
What hormones does the thyroid secrete?
thyroxine (T4) and trilodothyronine (T3)
Hyperthyroidism
high thyroid hormones
Symptoms of Hyperthyroidism
nervousness, thin skin/hair, weight loss, heat intolerance
Hypothyroidism
low thyroid hormones
Symptoms of Hypothyroidism
fatigue, poor memory, weight gain, cold intolerance
Medication used to treat hyperthyroidism
methimazole, propylthiouracil
Medication used to treat hypothyroidism
lecothyroxine
How does hyperthyroidism medication work?
inhibit synthesis of thyroid hormones
How does hypothyroidism medication work?
provides thyroid hormones (T3/T4)
Adverse effects of hyperthyroidism medication
fever, rash, low blood cell counts, hypothyroidism
Adverse effects of hypothyroidism medication
hyperthyroidism, osteoporosis, coronary artery disease
Hormones secreted by the pancreas
glucagon and insulin
How do hormones secreted by the pancreas affect the body?
increase or decrease glucose levels in the blood
Differences between type 1 and 2 diabetes
type 1 - autoimmune disorder destroys beta cells
type 2- insulin resistance
Complications of diabetes
nephropathy, neuropathy, retinopathy, impaired healing
How does metformin work?
promote glucose uptake by cells, decrease glucose production by liver, slow glucose absorption
Adverse effects of metformin
weight loss, GI upset, diarrhea, lactic acidosis in renal failure
Contraindications of metformin
type 1 diabetes, renal failure
Sulfonylureas common medications
glipizide, glyburide, glimepride
Adverse effects of sulfonylureas
hypoglycemia, weight gain, dizziness, loss of efficacy with further beta cell destruction
Contraindications of sulfonylureas
type 1 diabetes and renal elimination
Thiazolidindiones common medications
pioglitazone
Adverse effects of thiazolidindiones
hypoglycemia, edema, heart failure, factures, weight gain