Chapter 23 Flashcards
When is evolution apparent?
in changes in a population over time, not individual animals
What is microevolution? (2)
change in allele frequencies in a population over generations
Evolution in its smallest scale
What are the three main mechanisms of microevolution?
natural selection
genetic drift
gene flow
How does natural selection differ from genetic drift and gene flow in regards to microevolution?
The only mechanism that consistently improves the match between organisms and the environment
What is genetic drift?
chance events that alter allele frequencies
What is gene flow?
transfer of alleles between population
What is genetic variation?
Differences among individuals in the composition of their genes or other DNA sequences
How does genetic variation differ with the amount of genes?
Single gene- either-or effect is produced (purple or white flowers)
two or more genes- produces a difference in gradations along a continuum
How is gene variation quantified?
the average percentage of loci that are heterozygous
How can gene variation be measured in the molecular level?
nucleotide variation
Why doesn’t nucleotide variation always result in phenotypic variability?
differences occur within introns
What are five sources of genetic variation?
Mutation
Gene duplication
Production of new alleles and genes
Sexual reproduction
Produced rapidly by organisms with short generation times
How does new alleles arise?
mutation, or change in nucleotide sequence
Can mutations be predicted?
Cannot be predicted how and which DNA will be altered
Where does mutations occur, and how can it be passed down?
The majority of mutations occur in somatic cells in animals
Only mutations in gametes can be passed to offspring
What is point mutation, and an example?
change in one base
Ex- sickle cell disease
How beneficial or harmful are mutations?
Most mutations are slightly harmful
What is heterozygote protection?
when heterozygous individuals mask harmful recessive alleles
What is neutral variation?
point mutations in introns
How does gene duplication occur? (3)
Error in mitosis
Slippage during DNA replication
Activities of transposable elements
When are gene duplications harmful?
Large duplications can be harmful
How can small amounts of gene duplication affect genetic variation?
Smaller duplication may persist over generations and allow mutations
How is gene duplication correlated with evolution, and an example?
Played a major role in evolution
human ancestors had only one gene to smell, now we have 350
How can prokaryotes evolve quickly?
Prokaryotes have lower average mutations but have such more generations that variations arise quickly
Why is HIV so hard to cure?
HIV mutates even more quickly since it has short generation times and RNA genome, making Single-drug treatment is less effective
How does gene variation arise from sexual reproduction?
Gene variation results from combination of alleles from parents
Methods during sexual reproduction where gene variation arises (3)
Crossing over
Independent assortment of chromosomes
fertilization
What is a population, and how are they separated?
a group of individuals of the same species that live in the same area and interbreed to produce fertile offspring
isolated from others geographically
what is a gene pool?
all copies of every type of allele at every locus in all members of the population
What does a gene pool characterize?
Characterizes a population’s genetic makeup
What is frequency proportion?
number of specific allele/number of all allele x 100%
What is a fixed allele?
an allele existing for a particular locus in a population- all individuals are homozygous for this allele
What is the Hardy-Weinberg equilibrium? (2)
a population that is not evolving
Allele and genotype frequencies will remain constant from generation to generation- only if Mendelian segregation and recombination of alleles at work
What is the Hardy-Weinberg equation?
P2 (homozygous dominant) + 2pq (heterozygous) + q2 = 1
How does the Hardy-Weinberg equation signify equilibrium?
The actual population of homozygous dominant must equal p2 and so on for the population to be in equilibrium
What are the conditions for Hardy-Weinberg equilibrium? (5)
no mutation
random mating
no natural selection
extremely large population size
no gene flow
What happens if conditions of the Hardy-Weinberg equilibrium is not met?
evolution occurs
How does mutation allow evolution?
A gene pool is modified if mutations alter alleles or if entire genes are deleted or duplicated
How does non-random mating allow evolution?
If individuals mate within a subset population, such as inbreeding, random mixing of gametes does not occur, and genotype frequencies change
How does natural selection allow evolution?
Differences in survival and reproductive success of individuals carrying different genotypes can alter allele frequencies