Chapter 22: Abnormalities of the Placenta and Umbilical Cord Flashcards
Focal dilation of an artery
aneurysm
placenta where the lobes are nearly equal in size and the cord inserts into the chorionic bridge of tissue that connects the two lobes
bilobed placenta
fatal condition associated with multiple congenital anomalies and absence of the umbilical cord
body stalk anomaly
very rare condition where there is massive subchorionic thrombosis of the placenta secondary to extreme venous obstruction
Breus mole
Attachment of the placenta membranes to the fetal surface of the placenta rather than to the underlying villous placental margin
extrachorial placenta
bending, twisting, and bulging of the umbilical cord vessels mimicking a knot in the umbilical cord
false knot
Periumbilical abdominal wall defect, typically to the right of normal cord insertion that results in free-floating bowel within the amniotic fluid
gastoschisis
condition characterized by multiple complex fetal anomalies and a short umbilical cord
Limb-body wall complex
occurs when the umbilical cord inserts at the placental margin
marginal insertion or battledore placenta
central anterior abdominal wall defect at the site of cord insertion into the fetal abdomen that results in abdominal organs protruding outside the abdominal cavity but contained by a covering membrane consisting of peritoneum, Wharton jelly, and amnion
omphalocele
term that refers to a thickened or hydropic placenta
placentamegaly
Linear extra-amniotic tissue that projects into the amniotic cavity with no restriction of fetal movement
synechia (asherman syndrome)
intraplacental area of hemorrhage and clot
thrombosis
result of the fetus actually passing through a loop or loops of umbilical cord creating one or more knots in the cord
true knot
vascular structure connecting the fetus and placenta that normally contains two arteries and one vein surrounded by Wharton jelly
umbilical cord
Method of assessing the degree of umbilical cord coiling, defined as the number of complete coils per centimeter length of cord
umbilical coiling index (UCI)
failure of the normal physiological gut herniation to regress into the abdomen, resulting in a small amount of bowel protruding into the base of the umbilical cord
umbilical hernia
tubular, anechoic structures found beneath the chorionic plate that correspond to blood-filled spaces found at delivery
venous lakes
Decreased placental thickness is considered when placenta is less than ____
1.5 cm
inferior margin of the placenta is within 2 cm of the internal cervical os
low-lying placenta
placental tissue entirely covers the internal cervical os
placenta previa`
choriona villi adhere directly to but do not invade the myometrium
placenta accreta
chorionic villi invade the myometrium
placental increta
chorionic villi invade through the myometrium into the uterine serosa and potentially into surrounding tissues
placenta percreta
First trimester sonographic markers for ______ are:
gestational sac implantation in the lower uterine segment
multiple irregular vascular spaces within the placental bed
cesarean scar implantation of the gestational sac
morbidly adherent placenta
Late second and third trimester sonographer markers for ______ are:
placenta previa
multiple vascular lacunae within placenta
loss of normal hypoechoic retroplacental zone
abnormal uterine serosa-maternal bladder interface
morbidly adherent placenta
What is the placenta responsible for?
nutritive, respiratory, and excretory functions
used to describe appearance based on amount of placental calcifications and degree of maturation
placental grading
The placenta should be between __ cm and __ cm.
2
4
“jelly-like placenta”
IUGR
The placenta normally develops where chorionic villi interfacing the ______ grow.
decidua basalis
selective loss of parts of placenta and growth of other parts
presumed to occur beauce placenta preferentially grows where there is sufficient decidua and vascular supply and atrophies where condition less favorable
trophoblastic trophotropism
presence of one or more small accessory lobes that develop in membranes at a distance from periphery of main placenta
succenturiate lobe
ring shaped placenta
annular placenta
Annular placenta and PM are associated with ______
placenta previa
placenta extending beyond limits of chorionic plate with attachment of placental membranes to the fetal surface of the placenta, inward from the edge, rather than to underlying villous placenta margin
placenta extrachorialis
2 types of placenta extrachorialis
placenta circummarginate
placenta circumvallate
fetal membrane insertion is flat
may be found in 20% of placentas
placenta circummarginate
transition where fetal membranes of chorionic plate terminate; has a rolled or raised edge
placenta circumvallate
implantation of placenta into lower part of the uterus covering internal cervical os, thus delivering before fetus
placenta previa
irregular subchorionic marginal cystic structures or infolding of placental margin with a thick, curled peripheral edge
placenta circumvallate
linear structure protruding into fluid-filled amniotic cavity
placenta circumvallate
inferior margin of placenta covers internal cervical os
placenta previa
inferior margin within 2 cm of internal os
low-lying placenta
abnormal implantation of placental into uterine wall
morbidly adherent placenta
involves a defect in the decidua basalis; allows chorionic villi to invade the myometrium
morbidly adherent placenta
occurs when the chorionic villi becomes abnormally adherent to uterine myometrium rather than uterine decidua; accounts for about 75% of cases
placenta accreta
occurs when there is villous infiltration into the myometrial surface; occurs in 18% of cases
placenta increta
chorionic villi infiltrate and penetrate through entire myometrium, breaching serosa, potentially invading surrounding maternal organs; occurs in 7% of cases
placenta percreta
Most common reason for emergency postpartum hysterectomy
morbidly adherent placenta
optimal time for delivery with MAPs
34-35 weeks after corticosteroid injection given
Two most important risk factors to MAPs
placenta previa
previous c-section
gestational sac embedded into cesarean section scar at level of internal cervical os at base of maternal urinary bladder
cesarean section scar implantation
Most common location of MAPs
anterior implantation in the lower uterine segment
irregular anechoic structures within placental parenchyma found beneath the chorionic plate
placental lakes
speculated to be end result of intervillous and subchorionic thrombosis; results from pooling and stasis of maternal blood in perivillous and subchorionic spaces
fibrin depositions
hypoechoic lesions in subchorionic area or within placental mass, or as linear echogenicities streaks within an anechoic lesions
fibrin depositions
intraplacental area of hemorrhage and clot
intervillous thrombosis
hypoechoic placental lesions of varying size that may contain linear echogenicities representing fibrin deposits
intervillous thrombosis
most commonly found midway between subchorionic and basal areas of placenta
intervillous thrombosis
massive subchorionic hematoma and thrombosis; heterogeneous and hypoechoic lesions
Breus mole
_______ may appear hypoechoic or show placental thinning
necrotic infarct
occurs as a result of obstruction of spiral arteries; usually found at periphery of placenta
placental infarction
most often found near the umbilical cord insertion under the thin amniotic layer covering the chorionic plate
subamniotic cysts/hematomas
result from rupture of chorionic (fetal) vessels close to umbilical cord insertion into placenta
subamniotic cysts/hematomas
two primary nontrophoblastic tumors
chorioangioma and teratoma
benign vascular malformation of the placenta arising from primitive chorionic mesenchyme
chorioangioma
can be associated with:
elevated maternal serum alfa-fetoprotein
beta-human chorionic gonadotropin levels
chorangioma
contain arteriovenous shunts that can lead to severe fetal complications
chorioangiomas
classifications of placental abruptions
retroplacental hemorrhage
intraplacental hemorrhage
marginal hemorrhage
subchorionic blood clot
sonographic diagnosis based on increased vascularity or a large feeding vessel inside tumor with same pulsation rate as umbilical cord
chorangioma
well-circumscribed hyperechoic or hypoechoic ovoid mass protruding from fetal surface of placenta near cord insertion
chorangioma
very rare; usually benign but can be highly malignant; may contain structures derived from three germ cell layers; complex mass of placenta with cystic and solid components; calcifications may be present
Teratoma
vascularization is supplied by fetal circulation through arteriovenous shunts from umbilical cord
chorangioma
premature separation of all or part of the placenta from underlying myometrium
placental abruption
What artery is the artery that a Doppler measurement taken from to assess chorangioma?
middle cerebral artery
Prognosis of placental abruption depends on:
degree of placental attachment
gestational age
Gravest prognosis of placental abruption
significant retroplacental hemorrhage involving over 30-40% of placenta
amnion is visible as a discrete free-floating membrane separate from the chorion surrounding the fetus
sonographic diagnosis of chorioamniotic separation
Most common fetal membrane abnormality structures or conditions
chorioamniotic separation
elevation resulting from subchorionic hemorrhage
membranes associated with multiple gestations and blighted ova
intrauterine synechiae
linear, extra-amniotic tissues that project into the amniotic cavity
amniotic sheets or intrauterine synechiae
sporadic condition that is thought to occur as a result of rupture of the amnion without rupture of chorion
amniotic rupture sequence or amniotic band syndrome
early rupture can result in malformations of cranium, central nervous system, face, and viscera
amniotic rupture sequence of amniotic band syndrome
In amniotic band syndrome, bands may tear or disrupt previously normally developed structures leading to:
congenital amputations
constriction rings
bizarre nonanatomic facial clefts
designation given to several disorders arising from either normal or abnormal fertilization of an ovum resulting in neoplastic changes in trophoblastic elements of developing blastocyst
Gestational Trophoblastic disease
classifications of gestational trophoblastic disease
complete or partial hydadatidform mole
metastic disease or choriocarcinoma
chorionic villi that are markedly hydropic and swollen; proliferation of the trophoblast cell resulting in excessive production of beta-human chorionic gonadotropin levels
complete hydadatidform mole; molar pregnancy
distention of uterine cavity by a heterogeneous echogenic mass with a snowstorm appearance; enlarged uterus filled with multiple variable-sized small anechoic cysts
molar pregnancy
absence of both amniotic fluid and a fetus
complete mole
presence of co-existing fetus along with an enlarged, thickened placenta with multiple cystic spaces
partial mole
represent deep growth of abnormal tissue into and beyond the myometrium
invasive mole
considered locally invasive non-metastasizing neoplasms
invasive mole
capable of metastasizing; appear as heterogeneous, echogenic, and hypervascular masses
choriocarcinomas
rare vascular placental anomaly; characterized by mesenchymal stem villous hyperplasia; presents as an enlarged placenta; may be mistaken for molar pregnancy
placental mesenchymal dysplasia
placentomegaly; dilatation of chorionic vessels; large areas of cystic villous changes along with areas of normal placenta
placental mesenchymal dysplasia
The umbilical cord normally contains ___ arteries and ___ veins surrounded by Wharton jelly, all enclosed in a layer of amnion.
2, 1
one of the most common congenital anomalies of the umbilical cord
single umbilical artery
possible mechanisms of SUA
primary agenesis of one artery
atrophy or atresia of a previously present artery
persistence of original allantoic artery in body stalk of embryo
The ____ umbilical artery is more commonly absent.
left
presence of more than 3 vessels
supernumerary vessels
exclusively associated with conjoined twinning
supernumerary vessels
may represent an abnormal splitting of umbilical vessels between the 3rd and 5th week of development
supernumerary vessels
condition where right umbilical (portal) vein, rather than left-sided umbilical vein, remains open
persistent right umbilical vein
umbilical cord vein curves toward left-sided stomach rather than toward liver; gallbladder located medial to vein rather than lateral
persistent right umbilical vein
a focal dilatation of umbilical vein
umbilical vein varix