Chapter 18 - The Endocrine System Flashcards
The endocrine system acts with what other system to control all body systems?
Nervous system
Compared to the nervous system, the endocrine takes longer to? The effects, however, last _______ and influence what?
Cause a response / longer, a broader area of the body
The endocrine system releases these chemical substances that enter the bloodstream and travel to target cells where they exert effects by binding to receptor sites.
Hormones
The endocrine system consists of these ductless glands that release hormones.
Endocrine glands
The endocrine system consists of? (2)
Endocrine glands & several other organs and tissues that contains cells that secrete hormones.
Name the endocrine glands (5)
Pituitary, pineal, thyroid, parathyroid, adrenal glands
Glands that are not classified as endocrine glands, but they still secrete hormones (13)
Hypothalamus, ovaries, testes, kidneys, stomach, liver, pancreas, small intestine, thymus, heart, skin, adipose tissue, placenta
Hormones help to regulate? (5)
CHEMICAL composition and VOLUME of body fluids, metabolism and energy BALANCE, CONTRACTION of smooth and cardiac muscle fibers, SECRETION of glands, some IMMUNE system activities
Name 3 functions of hormones.
CONTROL growth and development, REGULATE operation of the reproductive system, help establish CIRCADIAN rhythms
How do hormones influence their target cells?
By binding to their receptors (typically protein)
Most target cells have how many receptors for a specific hormone?
2,000 - 100,000
If a hormone is prevented from binding with a receptor, what happens?
It cannot carry out its normal function.
What eventually happens to most hormones?
They are inactivated by the liver and excreted by the kidneys.
Most of these types of hormones are attached to transport proteins which make the hormones water-soluble long enough to circulate to the target cells.
Lipid-soluble hormones
Where are the receptors for lipid-soluble hormones located?
Inside of the target cells
These types of hormones circulate freely in the blood plasma.
Water-soluble
Example of a water soluble hormone.
Insulin
Where are receptors for water-soluble hormones located?
In the plasma membrane of target cells
Hormone secretion is regulated by what 3 things?
SIGNALS from the nervous system, CHEMICAL CHANGES in the blood, OTHER hormones
What is the main link between the nervous and endocrine systems?
The hypothalamus
What is the master endocrine gland?
The pituitary gland
What is the pituitary gland attached to?
The hypothalamus
The pituitary gland secretes hormones that do what?
Regulate other endocrine glands.
The pituitary gland consists of two of these? They are called?
Lobes / a large anterior and smaller posterior
The hypothalamus produces and releases these two types of hormones?
Releasing and inhibiting hormones
Releasing hormones cause the pituitary gland to?
Release hormones
Inhibiting hormones does what to the pituitary gland?
Suppresses the release of pituitary hormones
This hormone stimulates growth of body tissues.
Human growth hormone (hGH)
This hormone stimulates the synthesis and secretion of thyroid hormones.
Thyroid-stimulating hormone (TSH)
These hormone stimulates the ovaries and testes.
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
This hormone helps stimulate milk secretion by the mammary glands in females and has an unknown function in males.
Prolactin (PRL)
This hormone influences the production and secretion of certain hormones of the adrenal cortex.
Adrenocorticotropic hormone (ACTH).
This hormone may cause darkening of the skin; its exact role in humans is unknown.
Melanocyte-stimulating hormone
While the posterior pituitary gland does not synthesize hormones, it does store and release what two hormones?
Oxytocin (OT) & antidiuretic hormone (ADH)
This hormone that is produced in the hypothalamus and stored and released by the posterior pituitary gland stimulates contractions of the uterus in pregnant females and the ejection of milk.
Oxytocin (OT)
The synthetic form of this hormone is sometimes given to induce labor.
Synthetic OT (Pitocin)
This hormone is stored in the posterior pituitary gland and conserves body water, decreases urine volume and perspiration, and increases blood pressure.
Antidiuretic hormone (ADH)
Endocrine system disorders often involve?
Inadequate release of a hormone (hyposecretion) or excessive release of a hormone (hypersecretion)
This is the inadequate release of a hormone.
Hyposecretion
This is the excessive release of a hormone.
Hypersecretion
When there is an endocrine system disorder, sometimes the problem involves?
The hormone receptors
This hormone indirectly causes body cells to grow and multiply. For example, increased growth of bones and muscles during childhood and teenage years, maintenance of bones and muscles and healing/repair of tissues during adulthood.
Human growth hormone (hGH)
This hormone causes a decrease in the breakdown of proteins for energy, but an increase in the breakdown of lipids.
Human growth hormone (hGH)
This hormone helps to keep blood glucose levels at a proper level.
Human growth hormone (hGH)
This is caused by the secretion of too little hGH. The body fails to grow to an adult size.
Pituitary dwarfism
This is caused by the secretion of too much hGH during childhood. The long bones increase in length so the individual grows to be very tall.
Giantism
In giantism, body proportions are?
Normal
This is a butterfly-shaped gland located below the larynx (voice box) on the anterior portion of the trachea (windpipe).
Thyroid gland
These gland is highly vascularized.
Thyroid & adrenal glands
The thyroid gland produces what 3 hormones?
Thyroxine (T4), triiodothyronine (T3), calcitonin (CT)
This hormone produced by the thyroid gland contains 4 atoms of iodine and is lipid soluble.
Thyroxine (T4)
This hormone produced by the thyroid gland contains 3 atoms of iodine and is lipid-soluble.
Triiodothyronine (T3)
T3 and T4 exert effects where in the body? H is this made possible?
Throughout the body / most body cells have receptors for these hormones
T3 and T4 hormones regulate what 3 things?
BASAL metabolic rate, CELLULAR metabolism, and GROWTH and development
Calcitonin does what to blood calcium levels? It achieves this?
Lowers / decreases bone breakdown by increasing bone building by inhibiting osteoclasts and stimulating osteoblasts.