Chapter 16 Vocab Flashcards

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0
Q

Differentiation

A

The process by which a cell or group of cells becomes specialized in structure and function.

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1
Q

Model Organism

A

A particular species chosen for research into broad biological principles because it is representative of a larger group and usually easy to grow in a lab.

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2
Q

Morphogenesis

A

The development of the form of an organism and its structures.

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3
Q

Cytoplasmic Determinant

A

A maternal substance, such as a protein or RNA, that when placed into an egg influences the course of early development by regulating the expression of genes that affect the developmental fate of cells.

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4
Q

Induction

A

The process in which one group of embryonic cells influences the development of another, usually by causing changes in gene expression.

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5
Q

Determination

A

The progressive restriction of developmental potential whereby the possible fate of each cell becomes more limited as an embryo develops. At the end of determination, a cell is committed to its fate.

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6
Q

Apoptosis

A

A type of programmed cell death that is brought about by activation of enzymes that break down many chemical components in the cell.

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7
Q

Pattern Formation

A

The development of a multicellular organism’s spatial organization, the arrangement of organs and tissues in their characteristic places in three-dimensional space.

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8
Q

Positional Information

A

Molecular cues that control pattern formation in an animal or plant embryonic structure by indicating a cell’s location relative to the organism’s body axes. These cues elicit a response by genes that regulate development.

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9
Q

Homeotic Gene

A

Any of the master regulatory genes that control placement and spatial organization of body parts in animals, plants, and fungi by controlling the developmental fate of groups of cells.

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10
Q

Embryonic Lethal

A

A mutation with a phenotype leading to death of an embryo or larva.

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11
Q

Maternal Effect Gene

A

A gene that, when mutant in the mother, results in a mutant phenotype in the offspring, regardless of the offspring’s genotype. Maternal effect genes, also called egg-polarity genes, were first identified in Drosophila melanogaster.

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12
Q

Egg Polarity Gene

A

A gene that helps control the orientation (polarity) of the egg; also called a maternal effect gene.

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13
Q

Bicoid

A

A maternal effect gene that codes for a protein responsible for specifying the anterior end in Drosophila melanogaster.

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14
Q

Morphogen

A

A substance, such as Bicoid protein in Drosophila, that provides positional information in the form of a concentration gradient along an embryonic axis.

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15
Q

Totipotent

A

Describing a cell that can give rise to all parts of the embryo and adult, as well as extraembryonic membranes in species that have them.

16
Q

Stem cell

A

Any relatively unspecialized cell that can produce, during a single division, one identical daughter cell and one more specialized daughter cell that can undergo further differentiation.

17
Q

Pluripotent

A

Describing a cell that can give rise to many, but not all, parts of an organism.

18
Q

Oncogene

A

A gene found in viral or cellular genomes that is involved in triggering molecular events that can lead to cancer.

19
Q

Proto-oncogene

A

A normal cellular gene that has the potential to become an oncogene.

20
Q

Tumor suppressor gene

A

A gene whose protein product inhibits cell division, thereby preventing the uncontrolled cell growth that contributes to cancer.

21
Q

Ras gene

A

A gene that codes for Ras, a G protein that relays a growth signal from a growth factor receptor on the plasma membrane to a cascade of protein kinases, ultimately resulting in stimulation of the cell cycle.

22
Q

P53 gene

A

A tumor-suppressor gene that codes for a specific transcription factor that promotes the synthesis of proteins that inhibit the cell cycle.