Chapter 16: DNA replication Flashcards
Griffith
Bacterial Transformation
Chargoff
The base-pair rule
Avery
DNA was the hereditary material of viruses
Wilkens + Franklin
Determined the shape of DNA from X-rays
Watson + Crick
Established the entire structure of DNA
1st step of reconstruction
DNA is unzipped using HELICASE
2nd step of reconstruction
Polymerase travels down 3’ to 5’, adds nucleotides, and bonds sugars and phosphates together
3rd step of reconstruction
Okazaki fragments are bonded by ligase
Helicase
Unzips DNA during replication
DNA Polymerase
Adds nucleotides, bonds sugars and phosphates
Lagging End
replicated in the 5’ to 3’ direction in discontinous chunks
Leading End
replicated in the 3’ to 5’ direction continously
Nucleotide
Contains a sugar, phosphate, and base (ATGC)