Chapter 15: Chromosomal Inheritance

Question 1

Chromosomal Theory of Inheritance

Answer 1

states that chromosomes are carriers of genetic information

Question 2

Karyotype

Answer 2

Shows all chromosomes in an organism, organized by size

Question 3

Disorders that are recessive are…

Answer 3

masked in females by the other X chromosome

Question 4

Human Sex Linked Disorders

Answer 4

Colorblindness, Muscular Dystrophy, Hemophilia, Fragile X Syndrome

Question 5

Muscular Dystrophy

Answer 5

Wasting away of muscles, life expectancy is 20 years, females can carry this disease (pass it to sons)

Question 6

Hemophilia

Answer 6

“bleeders disease”, blood doesn’t clot properly, disease was present in the royal family (queen Victoria)

Question 7

Fragile X Syndrome

Answer 7

Caused by triplet repeats (duplication mutation) in a gene on the X chromosome, causes mental retardation, tip of the X chromosome seemed to be attached only by a small thread

Question 8

Non-Disjunction

Answer 8

Changes the chromosome #

Question 9

Down Syndrome

Answer 9

extra chromosome in #21

Question 10

Trisomy-18 (Edwards syndrome)

Answer 10

Extra copy of chromosome #18, Failure to grow/gain weight, developmental delays and intellectual disability, physical appearance (malformed ears, small jaw, narrow eyes)

Question 11

Trisomy-13 (Patau Syndrome)

Answer 11

An extra copy of chromosome #13, 50% of babies die in the first month

Question 12

Chromosome Mutations

Answer 12

Deletion, Duplication, Inversion, Translocation

Question 13

Cri Du Chat

Answer 13

Deletion of gene on chromosome #5