Chapter 14 Flashcards
What happens in M phase?
Mitosis and cytokinesis
How long does M phase last?
About 1 hour
What does M phase consist of?
prophase, prometaphase, metaphase, anaphase, telophase, cytokinesis
What happens in interphase?
Replications of chromosomes, prepares for cell division
How long is interphase?
Days, weeks, or longer
What does interphase consist of?
G, S, G2
What happens in G1?
Metabolic activity and growth
When does G1 take place?
Between end of mitosis and beginning of DNA replication
What happens in S phase?
DNA replication, growth, metabolic activity
What happens in G2 phase?
Metabolic activity, growth, prep for cell division
When does G2 happen?
Between end of S and beginning of mitosis
3 types of cell cycles in vivo:
- nerve cells, muscle cells, rbc
- liver cells and lymphocytes
- skin, epithelia, plant apical meristems
Nerve cell, muscle cell, rbc cell cycle:
Highly specializedm lack ability to divide
Liver cells and lymphocyte cell cycle:
Cells that do not normally divide but can be induced to divide if given stimulus
Skin, epithelia, plant apical meristem cell cycle:
Cells that normally posses high level of mitosis
What is the major control of cell cycle?
Initiation of DNA replication of mitosis
What protein is essential in control of cell cycle?
Protein kinases
What triggers M phase?
Activation of a protein kinase maturation promoting factor (MPF)
What are the two subunits of MPF?
Protein kinase and regulatory subunit cyclin
What activates protein kinase?
Increased concentration of cyclin
Progress of cell cycle monitored through: (3)
1) Sensors
2) Transmitters
3) Effectors
What do sensors do in cell cycle monitoring?
Detect chromosome abnormalities