Chapter #13 - Homeostasis Flashcards
Homeostasis
Maintaining a constant internal enviornment.
What internal enviornments are kept constant in our bodies?
- Temperature
- Amount of water
- Blood glucose concentration.
Why is temp. kept constant in the body?
Around 37 degrees celcius because it is the optimum for enzymes.
Why is water kept constant in the body?
So that cells are not damaged by losing/gaining water through osmosis.
Why is blood glucose concentration kept constant in the body?
- Cells need a steady amount of glucose to respire, or they will not be able to release the energy needed.
- Too much glucose in the blood can cause water to leave the cells via osmosis. Then they cannot carryout metabolic reactions.
What is blood glucose conc. controlled by?
Controlled by hromones secreted by the pancreas.
Set point
The normal value or range of values for a particular parameter - for example, the normal range of blood glucose conc. or the normal body tmp.
What is the normal blood glucose concentration?
Normal blood glucose conc. is 0.8 - 1.1 mg/cm^3 of blood (this is a range and is not constant).
Negative feedback
A mechanism that detects a move away from away from the set point and bring about the actions that take the values back towards the set point.
How does the pancreas contribute to homeostatis.
It has islets which produce two hormones which hlep control glucose concentration in blood. These islets are scattered around the pancres.
How does the body respond to an increase in blood glucose conc?
- Pancreas secretes insulin into blood, which reaches the liver.
- Causes liver to abdsorb glucose from blood and store it as glycogen. (an insoluble polysaccharide.)
=> Small amount oif glucose is used for resoeration (not stored).
Polysaccharide
Something with more than molecules (e.g. proteins).
How does the body respond to insulin?
Causes liver to absorb glucose from th blood and store it as the blood and store it as glycogen.
How does the body respond to an decrease in blood glucose conc?
- If blood glucose conc. falls too low, the pancreas secreted glucagon.
- This cause liver cells to break down glyccogen to glucose an release it into the blood.
What is type one diabetes?
A condition in which insuffivient insulin is secreted by the pancreas, so that blood glucose conc. is nor controlled.
Is negative feedback instantaneous?
No, it takes a short time for the body to detect change in internal enviornment, and then more time to implament corrective measure and for the corrctive measure to start working. Only then will the internal enviornment return to the set point.
Is the internal enviornmet always constant?
No, because negative feedback is not instantaneous so the lag, causes the internal enviornment to vary around the set point.
What is type 1 diabetes throught to be a result of?
The body’s imune system attcaking itself.
When does type 1 diabetes usually develop?
In childhood
When does type 1 diabetes affect people (what time of the day)?
- After eating meal (carb) blood glucose increases.
- Between meals.
What happens when people with type one diabetes have a meal (especially a high carb one)?
- Blood glucose increases
- But there is no sighn of secretion of insulin.