Chapter 12 Flashcards
genome
a cells DNA, its genetic information
chromosomes
packages of DNA molecules
chromatin
entire complex of DNA and proteins that is the building material of chromosomes
somatic cells
all body cells except the reproductive cells
gametes
reproductive cells
sister chromatids
joined copies of the original chromosome
centromere
a region made up of repetitive sequences in the chromosomal DNA where the chromatid is attached most closely to its sister chromatid
mitosis
division of genetic material in the nucleus
cytokinesis
division of the cytoplasm
cell cycle
the life of a cell from the time it is first formed during the division of a parent cell until its own division into two daughter cells
mitotic phase
includes both mitosis and cytokinesis; shortest part of cell cycle
G1 phase
first gap
G2 phase
second phase
S phase
synthesis
prophase
chromatin condensed
metaphase
centromeres go to opposite poles
anaphase
separates ta the centromere
telophase
two daughter nuclei form
cytokinesis
cytoplasm is split and two cells are formed
mitotic spindle
structure consists of fibers made out of microtubules and associated proteins; forms in cytoplasm during prophase
centrosome
subcellular region containing material that functions throughout the cell cycle to organize the cells microtubules
metaphase plate
imaginary plate midway between spindle’s two poles
cleavage furrow
a shallow groove in the cell surface near the old metaphase plate
binary fission
division in half; asexual reproduction of single-celled eukaryotes
origin of replication
specific place on the chromosome where the process of cell division is initiated and the DNA of the bacterial chromosome begins to replicate
cell control system
cyclically operating set of molecules in the cell that both triggers and coordinates key events in the cell cycle
checkpoint
control point where stop and go-ahead signals can regulate the cycle
cyclin
a protein that gets its name from its cyclically fluctuating concentration in the cell
growth factor
protein released by certain cells that stimulates other cells to divide
density-dependent inhibition
a phenomenon in which crowded cells stop dividing
benign tumor
tumors that do not cause serious problems
malignant tumor
includes cells whose genetic and cellular changes enable them to spread to new tissues and impair the functions of one of more organs
metastasis
the spread of cancer cells to locations distant from their original site