Chap 21 Flashcards
Poison
Any substance that can harm the body by altering cell structure or functions
Can be corrosive or irritant, destroying skin and other body tissues.
Poisonous gas can act as a suffocating agent, displacing oxygen in the air
Systemic poisons causing harm to the entire body or to an entire body system.
These poisons can critically depress or overstimulate the central nervous system, causing vomiting And diarrhoea, prevent red blood cells from carrying oxygen or interfere with normal biochemical processes In the body at the level of the cell.
Factors. Nature of poison, concentration, how it entered the body, age weight and general health
Toxins
A poisonous substance secreted by bacteria, plants and animals
Botulism
Bacterial contaminants in food may produce toxins, some of which can cause deadly diseases
Poisons are classified into 4 types
Ingested poison
Inhaled poison
-volatile liquid chemicals - able to change very easily from a liquid into gas
Absorbed poison
- through unbroken skin
- many are corrosive or irritants that will injure the skin then be slowly absorbed
- Ex. Insecticides and agricultural chemicals
Injected poison
-Ex. Illicit drugs, snake fangs or insect stingers
Patient information assessment
What substance was involved
When did the exposure occur
How much was ingested
Over how long a period did the ingestion occur
What interventions has the patient, family, or well-meaning bystanders taken
What is the patients estimated weight
What effects is the patient experiencing from the ingestion
Common poison signs
Nausea and vomiting are two of the most common results of poison ingestion but you may also find altered mental status, abdominal pain, diarrhea, chemical burns around the mouth and unusual breath odors
Food poisoning
Food that has been improperly handled or cooked. Can be caused by several different bacteria that from when exposed to the right conditions.
Some food poisonings are the result of bacteria causing an infection in the patient (symptoms may occur a day or so after ingestion), other times it may be the result of toxins formed by bacteria that contaminate the food, and it is these toxins that result in symptoms (usually within hours of ingestion)
Signs and symptoms include nausea, vomiting, abdominal cramps, diarrhoea and fever
Activated charcoal
Works through adsorption, the process of one substance becoming attached to the surface of another
Activated charcoal is not an antidote; however through the adsorption or binding process in many cases it will prevent or reduce the amount of poison available for the body to absorb.
Many poisons but not all are adsorbed by activated charcoal
Medical direction will determine whether the use of activated charcoal is appropriate
Activated charcoal contraindications
Patient who cannot swallow obviously cannot swallow activated charcoal
Patients with altered mental status might choke on activated charcoal and aspirate it into lungs
Patients who have ingested acids or alkalis should not take activated charcoal because the caustic material may have severely damaged the mouth, throat and esophagus. Damage is already done
Patient who have accidentally swallow while siphoning gasoline should not be given activated charcoal. The patient will be coughing violently and possibly aspirating the gasoline
Activated charcoal isn’t indicated in cases of food poisoning
If patient refuses charcoal, notify medical direction and continue reassessment and care
Activated charcoal vs syrup of ipecac
A traditional treatment for poisoning used to be syrup of ipecac. This orally administered drug causes vomiting in most people with just one dose. When vomiting occurs, it results, on the average, in removal of less than one-third of the stomach contents. because ipecac is slow, is relatively ineffective, and has the potential to make a patient aspirate vomitus, it is rarely used today.
Activated charcoal is the first choice for health care providers in most poisoning and overdose cases
Dilution
Thinning down or weakening by mixing with something else. Ingested poisons are sometimes diluted by drinking milk or water. Dilution with water may slow absorption slightly, whereas milk may soothe stomach upset. Frequently advised for patients who, as determined by medical direction or poison control, do not need transport to a hospital
- An adult should drink 1-2 glasses of milk or water
- Child should typically be given 1/2 to one full glass.
Activated charcoal drug
Generic: activated charcoal
Trade: SuperChar, InstaChar, Actidose, Liqui-Char
Indications
-Poisoning by mouth
Contraindications
- Altered mental status
- Ingestion of acids or alkalis
- Inability to swallow
Medication form
- Premixed in water, frequently available in a plastic bottle containing 12.5 grams of activated charcoal
- Powered-should be avoided in the field
Dosage
- Adults and children: 1g activated charcoal/kg of body weight
- Adult 25-50g
- Pediatric 12.5-25g
Side effects
- Some patients have black stools
- Some patients may vomit, particularly those who have ingested poisons that cause nausea. If the patient vomits, repeat the dose once
Antidotes
A substance that will neutralize the poison or its effects. There are only a few genuine antidotes and they can be used only with very small number of poisons. Modern treatment of poisonings and overdoses consist primarily of prevention of absorption when possible (activated charcoal) and good supportive treatment (such as airway maintenance, administration of oxygen, treatment for shock). In a small number of poisonings, advanced treatment are administered in a hospital (antidotes and kidney dialysis.
Naloxone is a popular antidote
Naloxone
Generic: Naloxone
Trade: NARCAN
Indications
- Suspected narcotic overdose
- Coma of unknown cause
Contraindications
-Patient breathing adequately and able to maintain own airway
Form
-Liquid
Dosage
-0.4-2mg
Side effects
- May precipitate withdrawals in patients dependent on narcotics
Naloxone administration
- Obtain medical direction, either online or offline
- Inspect the patients nostrils to be sure there are no obstructions to intranasal administration
- Consider restraining the patient before drug administration if you believe the patient may become combative
- Attach the atomizer to syringe
- Push the atomizer gently but firmly into the nostril opening
- Push the plunger of the syringe firmly but briefly until the desired amount of liquid has been expelled from the syringe. Limit the amount of fluid administered at one time to 0.5ml per nostril
- Repeat as needed with the other nostril
- Record 5 R’s