CH.41 Storage and Delivery of Medical Gases Flashcards
Laboratory Gases
–are used for equipment calibration and diagnostic testing
Therapeutic Gases
–are used to relieve symptoms and improve oxygenation of patients with hypoxemia
Anesthetic Gases
–are combined with oxygen to provide anesthesia during surgery
Gas flammability: Inflammable
–gases burn and are rarely used for medical purposes
Gas flammability: Nonflammable
–gases do not burn, but some support combustion
Gas flammability: Oxygen
–is a nonflammable gas; it does not burn and will not explode
–supports combustion, making burning brighter, hotter, and faster
Atmospheric partial pressure (ATPD)
–the physical conditions for a given gas are at ambient temperature and 760 mm Hg pressure without any humidity
STPD
–standard temperature, pressure, and dry
Oxygen (O2)
–colorless, odorless, transparent, and tasteless
– STPD: density of 1.429 g/L, slightly heavier than air, not very soluble in water,
– at room temperature and 1 atm pressure, only 3.3 ml of O2 dissolves in 100 ml of water
–Nonflammable but greatly accelerates combustion
Burning Oxygen
– an increase in O2 percentage at a fixed total pressure
– an increase in total pressure of O2 at a constant gas concentration
–Both O2 concentration and partial pressure influence the rate of burning
Oxygen Production
–O2 is produced through one of several methods
– Most large quantities of medical O2 are produced by fractional distillation of atmospheric air
– Small quantities of concentrated O2 are produced by physical separation of O2 from air
Oxygen: Fractional Distillation
– Most common method
–Least expensive method
Oxygen: Physical Separation
–Method 1: molecular sieves absorb nitrogen, trace gases, and water vapor from air
–provides a concentrated mixture of more than 90% O2 for patient use
–Method 2: use a vacuum to pull air through a semipermeable plastic membrane allows O2 and water vapor to pass through at a faster rate than N2 from ambient air
–This system can produce an O2 mixture of approximately 40%
– called Oxygen Concentrators
–used primarily for supplying low-flow O2 in the home care setting
Producing Oxygen
– Alternative procedure is to convert O2 directly to gas for storage in high-pressure metal cylinders
–Produce O2 that is approximately 99.5% pure
– The remaining 0.5% is mostly N2 and trace argon
–US Food and Drug Administration standards require an O2 purity of at least 99%
Air
– yellow cylinders
– colorless, odorless, naturally occurring gas mixture
–Contains 20.95% O2, 78.1% nitrogen, and 1% trace gases
–At STPD: density is 1.29 g/L
–Medical grade air produced by filtering and compressing atmospheric air
– may be referred to in a medical setting as room air or ambient air
Air
–compressed air is supplied in cylinders that are very similar sized to oxygen cylinders
–Piped compressed air is commonly provided in hospital medical gas system
–smaller, portable air compressors are available for hospital or home use
Carbon Dioxide
– STPD: is a colorless and odorless gas with a specific gravity of 1.52, and 1.5 times heavier than air
– Does not support combustion
–Produce by heating limestone in contact with water
–The FDA purity standard for CO2 is 99%
CO2 mixtures
– Calibration of blood gas analyzers
– Diagnostic purposes in clinical laboratories
Helium (He)
– odorless, tasteless, nonflammable, and chemically and physiologically
– Density of 0.1785 g/L
–Commercially produced from natural gas through liquefaction to purity standards of at least 99%
–Must always be mixed with at least 20% O2
–Therapeutic use: Heliox- mixture of O2 and helium
—– manages severe cases of airway obstruction
—– decreases work of breathing. Lower density. Makes gas flow more laminar..
Nitric Oxide (NO)
–colorless, nonflammable, toxic gas that supports combustion
–exposure to high concentrations alone can cause methemoglobinemia, which can cause tissue hypoxia
–FDA approved for use in treatment of term and near-term infants with hypoxic respiratory failure
Nitrous Oxide (N2O)
– colorless gas with sightly sweet odor and taste
–clinically used as anesthetic agent
–must always be mixed with oxygen
– produced by thermal decomposition of ammonium nitrate