CH.1 Pharmacology Intro. Flashcards
Drugs
Any chemical that alters the organism’s functions or processes
Pharmacology
the study of drugs
Chemical name
chemical structure
Code name
experimental chemical shows potential
Generic name
assigned by USAN council when the drug shows therapeutic use NF
Official name
Trade name
-generic name when approved by the FDA
–brand name given by a particular manufacturer
–the name is always capitalized
Chemical Synthesis
most common source of drug plants,minerals, and animals contribute
Animal
thyroid hormone, insulin. pancreatic dornase
Plants
oils
Mineral
copper sulfate, mineral oil
IND stands for
Investigational New Drug approval
IND Phase 1
small number, healthy subjects
IND Phase 2
small number, subjects with disease
IND Phase 3
Large, multicenter studies
Therapeutic Potential: A
important (significant therapeutic gain over other drug
Therapeutic Potential: AA
important therapeutic gain, indicated for patients with AIDS. fast track
Therapeutic Potential: B
modest therapeutic gain
Therapeutic Potential: C
important options, little or no therapeutic gain
Orphan Drugs
Drugs used for rare diseases
Over-the-counter
OTC
Does not require prescription
Advantages of Aerosol
Aerosol given by inhalation
Smaller dose, fewer side effects
rapid onset, targets respiratory system, painless, relatively safe
Adrenergic agents
relaxes bronchial smooth muscles
Anticholinergic agent
relaxes bronchoconstriction
Mucoactive agents
breaks down secretions
Corticosteroids
controls airway inflammation
Anti-asthmatic agent
prevents onset of asthma symptoms
Antiinfective agents
fights infections
