CH.4

Question 1

misfolding of polypeptides is a serious problem in cells. Which of the following diseases are associated with accumulation of misfolded proteins?

Answer 1

• Alzheimer’s
• Parkinson’s
• diabetes

Question 2

the structural level of a protein least affected by a disruption in H bonding is the

Answer 2

primary level

Question 3

what maintains the secondary structure of a protein

Answer 3

h-bonds

Question 4

the function of each protein is a consequence of its specific shape. what is the term used for a change in three-dimensional shape on conformation Due to the disruption of hydrogen bonds, disulfide bridges, Or ionic bonds?

Answer 4

denaturation

Question 5

there are 20 different amino acids. What makes one amino acid different from the other

Answer 5

different side chain groups ( R group)Attached to the alpha carbon

Question 6

What would be an unexpected consequence of changing one amino acid in a protein consisting of 325 amino acid

Answer 6

• the Primary structure of a protein would be changed
• The tertiary structure of a protein would be changed
• The biological activity or function of a protein might be altered

Question 7

Which type of interaction stabilizes an alpha helixAnd beta-pleated sheets Structures of proteins?

Answer 7

H bonds

Question 8

Which bonds are createdDuring the formation of the primary structure of a protein?

Answer 8

peptide bonds

Question 9

Altering which levels of Structural organization could change the function of a protein

Answer 9

• primary
• secondary
• tertiary

Question 10

Finding two of the amino acid molecules to form a largerMolecule requires

Answer 10

The release of a water molecule

Question 11

all of the following contain amino acids except

Answer 11

Cholesterol

Question 12

what is the term used for A protein molecule that assist in the proper folding of another protein

Answer 12

chaperone

Question 13

dehydration reactions are used in the forming of which of the following compounds

Answer 13

• triacylglycerides
• polysaccharides
• proteins

Question 14

The R group or side chain group of the amino acid serine -CH2-OH. The R group or side chain of Expect to find these amino acid alanine in a globular protein an aqueous solution

Answer 14

alanine Would be in the interior and serine Would be on the exterior of the globular protein

Question 15

Upon chemical analysisA particular polypeptideWhat is found to contain 100 Amino acids.How many peptide bonds?

Answer 15

99

Question 16

At which level of a protein Our interactions between the side chains(R groups) most important?

Answer 16

tertiary

Question 17

Polysaccharides lipids and proteins are similar in that they

Answer 17

Are synthesized by monomers by dehydration reactions

Question 18

The alpha helix and beta pleated sheet Are both common and polypeptide forms found in which protein level

Answer 18

Secondary

Question 19

Enzymes are

Answer 19

Proteins

Question 20

The tertiary structure of a protein is the

Answer 20

Unique three-dimensional shape of a fully folded polypeptide

Question 21

A strong covalent bond betweenAmino acids that functionsIn maintaining a polypeptide’s

Answer 21

disulfide bond

Question 22

What method did Frederick Sanger use to elucidate The structure of insulin?

Answer 22

Analysis of amino acid sequence of small fragments

Question 23

How many different kinds of polypeptides Each composed of 12 amino acids could be synthesized

Answer 23

2012

Question 24

the bonding of 2 aa molecules to form a larger molecule requires

Answer 24

the release/removal of a water molecule