Ch.11 Fundamentals of Nervous System and Nervous Tissue Flashcards
What are the functions of the nervous system?
- Gather information
- Process ad interpret information
- Respond to information
Nervous system only really deals with what?
Muscles
The nervous system is organized based on what 2 locations?
- Central Nervous System (95% of nervous tissue)
2. Peripheral nervous system (5%)
What are the 2 functions of PNS?
Sensory and motor
Integration/interpretation of information only occurs where?
CNS
Afferent means?
Bringing something to the CNS from PNS.
Efferent means?
Going out to muscles and glands of the body from CNS
Motor system is divided again into what 2 systems?
Somatic nervous system- skeletal muscles-voluntary
Autonomic Nervous System- involuntary muscles and glands.
Autonomic is divided into what 2 systems?
- Sympathetic Division- fight or flight– help supply the skeletal muscles with the chemicals needed to perform task
- Parasympathetic Division- resting and digesting. keep us running smoothly without much energy use. Sleep uses a lot of this division.
What are the two types of nervous system cells?
- neurons
2. (neuroglia)-glia
Neurons are the main functional cells what is their job>
Transmit information throughout the nervous system.
Glia are supportive their job is to…
protect and watch over the neurons.
What are the 6 types of Glia?
- Astrocytes
- Microglia
- Ependymal Cells
- Oligodendtocytes
- Satelitte cells
- Schwann Cells
Which of the 6 types of Glia are part of the CNS?
- Astrocytes
- Microglia
- Ependymal Cells
- Oligodendtocytes
Which of the 6 types of GLia are part of the PNS?
- Satelitte cells
6. Schwann Cells
This is the most abundant glia in the CNS that supports and braces neurons. It lines blood capillaries. Blood brain barrier.
Astrocytes
This glia is part of the CNS and monitors health of neurons. Serve as immune system of the CNS. Immune cells outside CNS have the tendency to be over active.
Microglia
This type of glia is part of the CNS lines central cavities of the brain and spinal cord. It circulates CSF throughout the CNS.
Ependymal Cells
This type of Glia is part of the CNA and wraps around thicker axons to create insulating myelin sheaths.
Oligodendrytes
This type of Glia is part of the PNS and surrounds neuron cell bodies (nucleus). Sort of the astrocytes on the outside.
Satellite Cells
This type of Glia is part of the PNS and forms myelin sheath.
Equivalent to the oligocendrocytes.
Schwann Cells
What are the 4 characteristics that define a neuron?
- Conduct electrical impulses
- Extreme longevity
- Amiotic
- High Metabolic Rates
What is the anatomy of the neuron?
Complex cell with a cell body and 1 or more processes
What is the cell body of a neuron called? Describe it.
Soma.
Contain all the normal organelles of a cell except for cenrioles.
The rough ER of a neuron cell body is called?
Nissl Bodies
There are many microtubles and neurofilaments in a neuron cell why?
To support the shape and stability, to transport along the processes.
Clusters of cell bodies in CNS are ____.
Clusters of cell bodies in the PNS are ___.
Nuclei
Ganglia
These are arm like projections from neuron cell body.
Processes
Bundles of processes in the CNS are called ____.
Bundles of processes in the PNS are called _____.
Tracts
Nerves
What are the 2 types of processes?
Dendrites
Axons
These are short, tapering, branch like extensions almost like tree branches. They serve as the major receptive or input areas of the neuron because of their immense surface area.
Dendrites
Motor neurons have 100’s of _____.
dendrites
These are thorn like projections from dendrites.
dendritic spines.
Dendrites conduct information to cell body by ____ ____. (not action potentials)
Graded potentials
These are long threadlike part of a nerve cell along which impulses are conducted from the cell body to other cells
Axons
There are only ___ axons per neuron.
1
Axons extend from where?
Axon hillock
Axons are uniform in width until the ___ ___.
Terminal branches
Long axons are called what in the PNS?
Nerve Fibers
Axons can branch and end in 1000’s of ___ ____.
Terminal branches
What is the branch of an axon called?
Axon collaterals.
What is the end of the axon branch called?
Terminal Branch or synaptic boutons
This is the conducting region of the neuron. It generates nerve impulses (action potentials) and transmits them away from cell body to the axon terminal to the next neuron.
Axons
The axon terminal is also the ____ region of the neuron. When impulse reaches terminal neurotransmitters are released to excite or inhibit the next cell.
secretory
These are many long or large axons coated with a white fatty segmented covering called what?
Myelin sheath
Myelin protects and insulates ____ increasing the speed of transmission.
axons
This is the portion of Schwann cell containing nucleus and most of cytoplasm, on the outside surface of myelin sheath.
Neurilemma
These are the gaps between Schwann cells where the axon is exposed.
Node of Ranvier
In the CNS all the myelin is packed together is called
White Matter
Lots of cell bodies and dendrites, un-myelinated dendrites in the CNS is called.
Grey Matter
What are the 3 structural classifications of neurons?
- Multipolar
- Bipolar
- Unipolar
What are the 3 functional classifications of neurons?
- Sensory (Afferent)
- Motor (Efferent)
- Interneuron or association neuron
This is a branch of physiology and neuroscience that is concerned with the study of the functioning of the nervous system.
Neurophysiology
When stimulated neurons generate ____ ____ (action potential) that travel the length of the axon.
electrical impulses
The action potential is always the ____ no matter what stimulus started it.
same
Opposite electrical charges attract in the body ____ is required to keep them separate. When opposite charges come together energy is released.
energy
This is the measure of potential energy caused by the separation of electrically charged particles.
Voltage
This is the difference in voltage between 2 points.
Potential
This is the flow of electrical charge from one point to another.
Current
This is a hinderance to charge flow.
Resistance
What is Ohms Law?
current=voltage/resistance
Electrical currents in the body are the movement of ___.
Ions
Stored energy that can be used to do work.
Potential energy
Cells of the body can move ions to seperate ____ and ____ charges.
positive
negative
This has many large proteins that serve as channels for ions to enter and leave the cell.
Membrane Ion Channels
Most Membrance Ion Channels are “gated” which means what?
They are blocked and waiting for the right “key” or signal.
These Membrane Ion Channels require a chemical “key”.
Ligand-Gated Channel
These Membrane Ion Channels require Changes in membrane potential.
Voltage Gated Channels
These Membrane Ion Channels require physical deformation (touch and pressure receptors).
Mechanically Gated Channels
These Membrane Ion Channels are always open.
Leakage Channels
Ions move along concentration and electrical gradients ( electrochemical gradients)
Voltage Gated Ion Channels
Movement of ions creates what?
electrical current
The inside of the neuron is more negative than the outside.
Resting membrane potential.
What is the membrane potential of a neuron at rest?
-70mV
Membrane is impermeable to large anionic molecules (A-). _____ is most important for generating resting membrane potential.
Potassium (K+)
How can membrane potential be altered?
- Change the permeability or movement of Ions across the membrane.
- Change ion concentration
What are the two types of membrane potential signals?
- Graded potentials
2. Action potentials
These are incoming signals that are a short distance.
Graded potenitals.
What are the 2 types of graded potential?
- Depolarization
2. Hyperpolarization
This is where the membrane becomes more positive than at rest and increases the chance of nerve impulse.
Depolarization
This is where the membrane becomes more negative than at rest and decreases the chance of a nerve impulse.
Hyperpolarization
Current decreases in magnitude with distance from a stimulus and flows in all directions away from the stimulus.
Graded potential
What causes a graded potential?
Opening a gated ion channel
When stimulus is a neurotransmitter, graded potential is called what?
Postsynaptic potential
Only excitable membranes can generate this type of potential?
Action
This is the brief reversal of membrane potential. (-70mV to +30mV)
Action potential
Which gated channel does action potential use which opens and closes allowing Na+ and K+ to move.
Voltage Gated Channels
During action potential events this is when the voltage gated channel is closed.
Resting state
During action potential events this is increased Na+ permeability and reversal of membrane potential.
Depolarization
During action potential events the decrease in Na+ permeability as slower inactivation gate closes in the channel. Increase in K+ permeability as voltage gated K+ channels open and K+ rushes out of neuron.
Repolarization phase
During action potential events, K+ efflux undershoots resting membrane potential (after hyperpolarization)
Hyperpolarizing phase
The repolarization restores what?
Electrical Balance
The sodium potassium pump restores what?
Ion Balance