Ch 9

Question 1

Enterobacteriaceae character is ?

Answer 1

Largest , Gram-negative, non-spore-forming rods, Facultative anaerobes , Ferment glucose, reduce nitrate, catalase-positive, oxidase-negative, Normal intestinal flora in humans and animals , organisms in soil, water, and vegetation

Question 2

Animal reservoirs is ?

Answer 2

Salmonella, Yersinia

Question 3

Human carriers is ?

Answer 3

Shigella, Salmonella Typhi

Question 4

Endogenous spread is ?

Answer 4

E. coli from gut to peritoneum

Question 5

Lactose non-fermenters is ?

Answer 5

Salmonella, Shigella, Yersinia

Question 6

Lactose fermenters is ?

Answer 6

E. coli, Klebsiella

Question 7

Lipopolysaccharide (LPS) major cell wall antigen is ?

Answer 7

▪ O polysaccharide: epidemiologic classification
▪ Core polysaccharide: common.
▪ Lipid A: endotoxin activity

Question 8

كيف تتحرك Enterobacteriaceae ؟

Answer 8

Fimbriae
Flagella (H antigen)

Question 9

O antigen is ?

Answer 9

somatic polysaccharides, species-specific

Question 10

K antigen is ?

Answer 10

capsular, interferes with O antigen detection

Question 11

H antigen is ?

Answer 11

flagellar, heat-labile, for motile species

Question 12

Endotoxin (Lipid A) released ?

Answer 12

upon cell lysis

Question 13

ماذا يحدث عند إفراز ال Endotoxin (Lipid A) ؟

Answer 13

❖ Complement activation, cytokine release, fever, leukocytosis
❖ Can lead to septic shock, thrombocytopenia, and disseminated
intravascular coagulation (DIC

Question 14

Capsules be ?

Answer 14

▪ Hydrophilic capsule repels phagocytes
▪ Protective role reduced if host produces specific antibodies

Question 15

Salmonella enterica typhi Distinguishing Features is ?

Answer 15

Gram-negative rods, highly motile with the Vi capsule, Facultative anaerobe , non–lactose fermenting, Produces H2S , Sensitive to acid

Question 16

Enteric (Typhoid) Fever Symptoms is ?

Answer 16

Fever, headache, myalgia, anorexia

Question 17

Septicemia Caused by ?

Answer 17

Salmonella Typhi, Salmonella Paratyphi,
Salmonella Choleraesuis

Question 18

(S. enteritidis, S. typhimurium)
Distinguishing Features

Answer 18

▪ Facultative gram-negative rods, non–lactose fermenting on EMB,
MacConkey medium
▪ Produces H2S, motile (unlike Shigella

Question 19

Disease by S. enteritidis, S. typhimurium?

Answer 19

Enterocolitis/gastroenteritis
Septicemia Meningitis Osteomyelitis
UTI and endocarditis or reactive arthritis complicates

Question 20

Enterocolitis/gastroenteritis symptoms ?

Answer 20

nausea; vomiting; only occasionally
bloody, loose stools; fever; abdominal pain; myalgia; headache

Question 21

UTI and endocarditis or reactive arthritis complicates symptoms?

Answer 21

Eye irritation, painful urination and painful joints

Question 22

What is Treatment of Salmonella ?

Answer 22

ampicillin, third-generation
cephalosporin, fluoroquinolone, Ciprofloxacin, or
TMP-SMX for invasive disease

Question 23

most severe disease of SHIGELLA is ?

Answer 23

Shigella dysenteriae

Question 24

Shiga toxin
Produced by?

Answer 24

S. dysenteriae, type 1

Question 25

Shiga toxin Three activities is ?

Answer 25

neurotoxic, cytotoxic, enterotoxic