Ch 2 Flashcards

1
Q

Gastroenteritis symptoms is

A

2-6 hours after ingesting toxin: nausea, abdominal pain, vomiting, followed by diarrhea

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2
Q

Gastroenteritis Pathogenicity Factors is

A

Enterotoxins A-E preformed in food

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3
Q

Infective endocarditis symptoms is

A

Fever, malaise, leukocytosis, heart murmur (may be absent initially)

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4
Q

Infective endocarditis Pathogenicity Factors is

A

Fibrin-platelet mesh, cytolytic toxins

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5
Q

Abscesses and mastitis symptoms is

A

Subcutaneous tenderness, redness and swelling; hot

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6
Q

Abscesses and mastitis Pathogenicity Factors is

A

Coagulase, cytolysins

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7
Q

Toxic shock syndrome symptoms is

A

Fever, hypotension, scarlatiniform rash that desquamates
(particularly on palms and soles), multiorgan failure

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8
Q

Toxic shock syndrome Pathogenicity Factors is

A

TSST-1

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9
Q

Impetigo symptoms is

A

Erythematous papules to bullae

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10
Q

Impetigo Pathogenicity Factors is

A

Coagulase, exfoliatins

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11
Q

Scalded skin syndrome symptoms is

A

Diffuse epidermal peeling

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12
Q

Scalded skin syndrome Pathogenicity Factors is

A

Coagulase, exfoliatins

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13
Q

Pneumonia Symptoms is

A

Productive pneumonia with rapid onset, high rate of necrosis, and high fatality; nosocomial, ventilator, postinfluenza, IV drug abuse, cystic fibrosis, chronic granulomatous disease, etc.
Salmon-colored sputum

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14
Q

Pneumonia Pathogenicity Factors is

A

Coagulase, cytolysins

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15
Q

Surgical infections symptoms is

A

Fever with cellulitis and/or abscesses

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16
Q

Surgical infections Pathogenicity Factors is

A

Coagulase, exfoliatins,
+ TSSTs

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17
Q

Osteomyelitis symptoms is

A

Bone pain, fever, + tissue swelling, redness; lytic bone lesions on imaging

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18
Q

Osteomyelitis Pathogenicity Factors is

A

Cytolysins, coagulase

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19
Q

Septic arthritis symptoms is

A

Monoarticular joint pain; inflamation

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20
Q

Septic arthritis Pathogenicity Factors is

A

Cytolysins, coagulase

21
Q

وين بتعيش ال S. hominis ؟

A

around apocrine sweat glands

22
Q

وين بتعيش ال S. capitis ؟

A

scalp, face, external ear

23
Q

Endocarditis due to

24
Q

مين يلي بسبب ال Endocarditis

A

S. epidermidis, S. lugdunensis

25
من الذي يسبب ال Prosthetic Joint Infections
S. epidermidis common in artificial hip and knee infections
26
ما هي أعراض ال Prosthetic Joint Infections ؟
localized pain and mechanical joint failure
27
الأعراض الغير الشائعة ل Prosthetic Joint Infections ؟
fever, leukocytosis
28
ما علاج ال Prosthetic Joint Infections ؟
joint replacement and prolonged antibiotic therapy
29
من يسبب Urinary Tract Infections ؟
S. saprophyticus
30
Urinary Tract Infections symptoms is
dysuria, pyuria, and bacteriuria
31
من يسبب ال Patients fitted with cerebrospinal fluid shunts (meningitis ؟
S. epidermidis
32
The most common cause of peritoneal dialysis–related
peritonitis
33
تعيش ال S. epidermidis في ؟
skin and mucous membranes
34
تعيش ال S. saprophyticus في ال ؟
skin, intestine, vagina; UTI
35
Penicillin-binding proteins (PBPs) catalyze
peptidoglycan synthesis
36
Teichoic acids is
Phosphate-containing polymers attached to peptidoglycan
37
Lipoteichoic acids is
Bound to lipids in the cytoplasmic membrane
38
Protein A is
Binds Fc region of IgG
39
Capsule & Slime Layer function is
Prevent phagocytosis
40
Protein A function is
Binds IgG Fc region → Inhibits opsonization
41
Complement Inhibitors function is
Complement Inhibitors
42
Cytolytic Toxins
Destroy leukocytes & host cells
43
Exfoliative Toxins (ETA, ETB): Cause
Staphylococcal Scalded Skin Syndrome
44
Enterotoxins (A-E, G-X): Responsible
food poisoning
45
Coagulase: Forms
fibrin clots, shielding bacteria (S. aureus
46
Hyaluronidase: Breaks down
connective tissue → Invasion
47
Fibrinolysin (Staphylokinase) function is
Dissolves clots → Bacterial spread
48
Lipases & Nucleases
Survival in sebaceous areas, degrade host DNA
49