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ميدكال > Ch 8 > Flashcards

Ch 8 Flashcards

1
Q

Pilus is ?

A

Aids attachment to human mucosal epithelium;
coonstant and hyper variable regions- analogous
to Igs that contribute to antigenic diversity in
gonococci

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2
Q

Por proteins is ?

A

Form pores through outer membrane; antigenic;
specific serotypes associated with virulence

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3
Q

Opa proteins is ?

A

Assist binding to epithelia cells

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4
Q

LOS is ?

A

Lipooligosaccharide (endotoxin activity)

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5
Q

Rmp proteins is ?

A

Inhibit cidal activity of serum

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6
Q

IgA protease is ?

A

Core contains enzyme; released by cell to
destroy IgA1

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7
Q

B serogroups is ?

A

is not strongly immunogenic (sialic acid)

used for serogrouping, detection in CSF, and vaccine

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8
Q

IgA protease allows ?

A

oropharynx colonization

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9
Q

Endotoxin (lipooligosaccharide) macke ?

A

fever, septicemia, septic shock and DIC
in meningococcemia, overproduction of outer membrane

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10
Q

شو الأمراض يلي بتسببهم Neisseria meningitidis ؟

A

Meningitis
Pneumonia
Meningococcemia

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11
Q

Meningococcemia is ?

A

rapid sepsis, shock,
purpura, rash that is generally petechial

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12
Q

Meningitis CSF analysis be ?

A

Increased WBCs, decreased glucose, high protein

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13
Q

Neisseria meningitidis Treatment is ?

A

Ampicillin and cefotaxime (neonates/infants); cefotaxime or ceftriaxone with
or without vancomycin (children and adults

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14
Q

Outer membrane proteins in Neisseria gonorrhoeae is ?

A

OMP I
Opa proteins
IgA protease

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15
Q

OMP I is ?

A

structural, antigen used in serotyping

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16
Q

Opa proteins (opacity) is ?

A

antigenic variation, adherence

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17
Q

IgA protease is ?

A

aids in colonization and cellular uptake

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18
Q

Urethritis is ?

A

Painful urination, Pain or swelling in one testicle,
Pus-like discharge from the tip of the penis

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19
Q

Endocervicitis, PID (contiguous spread) is ?

A

Increased vaginal discharge, Painful urination,
Vaginal bleeding between periods, such as after
vaginal intercourse, Abdominal or pelvic pain

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20
Q

Ophthalmia neonatorum is ?

A

(Rapidly leads to blindness if untreated)

21
Q

Eye infection is ?

A

Conjunctivitis (eye pain, sensitivity to light, and pus-
like discharge from one or both eyes

22
Q

Gonococcal pharyngitis is ?

A

sore throat and swollen lymph nodes in the neck.

23
Q

Proctitis is ?

A

Anal itching, pus-like discharge from the rectum

24
Q

Arthritis is ?

A

(septic arthritis), the affected joints might be warm,
red, swollen and extremely painful, especially during
movement

25
Neisseria gonorrhoeae Culture is ?
Thayer-Martin medium
26
Colistin is ?
Inhibits gram-negative flora
27
Vancomycin is ?
Inhibits gram-positive flora
28
Nystatin is ?
Inhibits yeast flora
29
Trimethoprim is ?
Inhibits swarming Proteus
30
Treatment of N. gonorrhoeae is ?
Ceftriaxone + Azithromycin
31
شو بنعطي الأطفال لما ينولدوا ؟
nitrate, tetracycline, erythromycin
32
Neisseria sicca & Neisseria mucosa cause ?
meningitis, pneumonia, sinusitis
33
Eikenella corrodens Common in ?
bite wounds, endocarditis, pneumonia, brain abscesses
34
Kingella kingae Causes ?
septic arthritis in children, endocarditis
35
. sicca and N. mucosa are usually susceptible ?
penicillin
36
N. sicca and N. mucosa low-level resistance observed due to altered?
PBP2
37
Eikenella corrodens character ?
Nonmotile, non-spore-forming, facultatively anaerobic Colonizes human oropharynx and can cause subacute bacterial endocarditis Small, gram-negative rods
38
Poor or no growth on selective gram-negative media. Is ?
Eikenella corrodens
39
Bleach-like odor is ?
Eikenella corrodens
40
Eikenella corrodens Antibiotic Susceptibility is ?
Tetracyclines, fluoroquinolones Penicillin, ampicillin
41
Eikenella corrodens Resistant to?
Oxacillin Clindamycin, erythromycin, aminoglycosides
42
Kingella kingae is ?
Small gram-negative coccobacilli resembling Neisseria. Facultatively anaerobic, ferments carbohydrates
43
Kingella kingae Primary Clinical Significance is ?
Septic arthritis in children. Endocarditis in all age groups
44
Kingella kingae Antibiotic Susceptibility Effective Treatments is ?
Penicillin, tetracyclines, erythromycin. Fluoroquinolones, aminoglycosides
45
Moraxella catarrhalis Distinguishing Features is ?
Gram-negative diplococcus
46
Moraxella catarrhalis Transmission is ?
respiratory droplets
47
Moraxella catarrhalis Disease is ?
acute otitis media Sinus infection Pneumonia and Bronchitis Conjunctivitis (Pink eye) Meningitis In newborns (very rare cases
48
Moraxella catarrhalis Treatment is ?
Amoxicillin and clavulanate, second- or third-generation cephalosporin or Trimethoprim/ sulfamethoxazole (TMP- SMX
49

ميدكال (15 decks)

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