Ch. 7: Disorders of Blood Cells

Question 1

erythropoetin is made where?

Answer 1

in the kidneys

Question 2

reasons for anemia

Answer 2

1) failed production
2) Hemorrhage (blood loss)
3) hemolysis (destruction)

Question 3

what is fibrinogen involved in?

Answer 3

clotting

Question 4

what is immunoglobulins involved in?

Answer 4

immune reactions

Question 5

what are beta globulins involved in?

Answer 5

transport; reactant proteins

Question 6

what is albumin involved in?

Answer 6

transport; plasma osmotic pressure

Question 7

WBC: phagocytosis; immune reactions

Answer 7

monocytes

Question 8

WBC: immune reactions

Answer 8

lymphocytes

Question 9

platelets come from

Answer 9

megakaryocytes

Question 10

life span of RBCs

Answer 10

120 days; 3 months

Question 11

granulocyte life span

Answer 11

~4 days

Question 12

lymphocytes and monocyte life span

Answer 12

~7 days

Question 13

platelets life span

Answer 13

~7 days

Question 14

about how much more is hematocrit than hemoglobin?

Answer 14

3x as much

Question 15

color is mostly what for microcytic?

Answer 15

hypochromic (pale)

Question 16

chronic hemorrhage first produces anemia dure to what? then later?

Answer 16

1) hemorrhage

2) failed RBC production bc of iron deficiency

Question 17

chronic hemorrhage first produces anemia dure to what? then later?

Answer 17

1) hemorrhage

2) failed RBC production bc of iron deficiency

Question 18

excess RBC in blood

Answer 18

polycythemia (erythrocytosis)

Question 19

low plasma volume (dehydration) or “stress” polycythemia

Answer 19

relative polycthemia

Question 20

increased total body RBCs

Answer 20

absolute polycythemia

Question 21

low white cell count

Answer 21

leukopenia

Question 22

high white cell count

Answer 22

leukocytosis

Question 23

leukopenia examples

Answer 23

neutropenia and lymphopenia

Question 24

leukocytosis examples

Answer 24

neutrophilia and lymphocytosis

Question 25

leukemoid reaction

Answer 25

> 50,000 WBCs/mm^3

Question 26

enlarged nodes

Answer 26

lymphadenopathy

Question 27

inflamed nodes

Answer 27

lymphadenitis

Question 28

malignant cells in blood and BM; usually no mass

Answer 28

leukemia

Question 29

types of leukemia

Answer 29

acute (agressive) or chronic (indolent)

Question 30

malignant cells in a discrete mass, usually no circulating cells in blood

Answer 30

lymphoma

Question 31

malignant cells in a discrete mass, usually no circulating cells in blood

Answer 31

lymphoma

Question 32

abnormally small 22 is called what? what is it involved with?

Answer 32

philadelphia chromosome; chronic myeloid leukemia (CML)

Question 33

preleukemia syndrome

Answer 33

myelodysplasia

Question 34

acute more ( ) cells; chronic more ( ) cells

Answer 34

immature; mature

Question 35

lymphoid leukemias: most common malignancy of children, aggressive

Answer 35

ALL

Question 36

lymphoid leukemias: older individuals, most common leukemia, indolent course

Answer 36

CLL/SLL

Question 37

lymphomas: 10-30 yo, mediastinum and neck involved

Answer 37

Hodgkin

Question 38

Hodgkin cure rate

Answer 38

75-90%

Question 39

lymphomas: more aggressive but depends on the type (ex. follicular, diffuse, cell size)

Answer 39

Non-Hodgkin

Question 40

lymphomas: more aggressive but depends on the type (ex. follicular, diffuse, cell size)

Answer 40

Non-Hodgkin

Question 41

malignant cell of Hodgkin’s Disease

Answer 41

Reed-Sternberg Cell

Question 42

“punched out” lesions

Answer 42

multiple myeloma

Question 43

overactice, often enlarged spleen

Answer 43

hypersplenism

Question 44

tumor of the thymic epithelial cells

Answer 44

thymoma