Ch. 6 - Skin & Its Appendages Flashcards
What is the body’s largest organ?
Skin
What is the integumentary system?
Skin & its appendages (hair, nails & skin glands)
Skin is classified as ___________ membrane
cutaneous
List 2 primary layers of the skin
- epidermis
2. dermis
What layer does the hypodermis lie beneath?
Dermis
There are 2 types of skin - thick & thin. What does these types cover?
thin - covers most of body’s surfaces
thick - covers soles and palms
List the 4 types of epidermal cells
- keratinocytes
- melanocytes
- epidermal dendritic cells
- tactile epithelial cells
skin cell that is the principal structural element of the outer skin
keratinocyte
skin cell that constitues 90% of cells present
keratinocyte
skin cell that is sometimes called corneocytes after it is fully keratinized
keratinocyte
skin cell that contains melanin?
melanocyte
skin cell that produces pigment
melanocyte
skin cell that filters UV light
melanocyte
skin cell that plays a role in immune response
epidermal dendritic cells
skin cell that is also called langerhan cells
epidermal dendritic cells
skin cell that are branched antigen-presenting cells
epidermal dendritic cells
skin cell that attach to sensory nerve endings to form ‘light touch’ receptors
tactile epithelial cells
skin cell that are also called Merkel cells
tactile epithelial cells
list the 5 cell layers in epidermis (from deepest to superficial)
- stratum basale (base layer)
- stratum spinosum (spiny layer)
- stratum granulosum (granular layer)
- stratum lucidum (clear layer)
- stratum corneum (horny layer)
this epidermal layer contains single layer of columnar cells that undergoes mitosis - after which the cells migrate through the other layers until they are shed
stratum basale
epidermal layer that is rich in RNA
stratum spinosum
epidermal layer that is arranged in 8 to 10 layers with desmosomes that pull cells into spiny shapes
stratum spinosum
epidermal layer that can initiate protein synthesis for production of keratin
stratum spinosum
epidermal layer where cells are arranged in 2-4 layers and filled with keratohyalin granules
stratum granulosum
epidermal layer that contains high levels of lysosomal enzymes
stratum granulosum
epidermal layer where cells are filled with keratin precursor called eleidin
stratum lucidum
epidermal layer absent in thin skin
stratum lucidum
epidermal layer composed of dead cells filled with keratin known as the barrier area
stratum corneum
the time required for epidermal cells to form in the stratum basale and migrate to the skin surface is known as this:
turnover or regeneration time
what is the approximate length of regeneration time
35 days
what does epidermal growth factor regulate?
epidermal growth and repair
a shortened turnover time increases the thickness of stratus corneum and results in this:
callus formation
each group of 8-10 basal cells in mitosis with their vertical columns of migrating keratinocytes is called this:
epidermal proliferating unit
this epidermal component is a partial barrier to the passage of some cells and large molecules
dermoepidermal junction
this epidermal component is a basement membrane with a polysaccharide gel ‘glue’ that connects the epidermis to the dermis below
dermoepidermal junction
this is sometimes called the ‘true skin’
dermis
true or false.
the dermis is much thicker than the epidermis and lies beneath it
true
this gives strength to skin
dermis
this serves as a reservoir storage area for water and electrolytes
dermis
5 structures that are found in the dermis
- arrector pili muscles
- hair follicles
- sensory receptors
- glands (sweat and sebaceous)
- blood vessels
rich vascular supply plays a critical role in _____________ regulation
temperature
different receptors in the skin detect ________ & _____________
pain, pressure
2 layers of the dermis
- papillary layer
2. reticular layer
which dermal layer forms a unique pattern that gives finger prints?
papillary layer
which dermal layer is tough yet stretchable and produces leather
reticular layer
true or false.
The dermal layer continually sheds and regenerates itself just like the epidermal layer
false - it does not
what structures form scars during wound healing
fibroblasts
what are cleavage lines also known as?
langer’s lines
what is also called the subcutaneous layer or superficial fascia?
hypodermis
what connects skin to muscles below?
hypodermis
true or false.
hypodermis is part of the skin
false
2 types of melanin
- eumelanin
2. pheomelanin
what determines skin colour?
quantity, type & distribution of melanin
what releases melanin in packets called melanosomes?
melanocytes
type of injection that enters the skin at a 15 degree angle into the subcutaneous tissue
intradermal (ID)
type of injection that enters the skin at a 45 degree angle and goes beneath the subcutaneous tissue
subcutaneous (SQ)
congenital absence of melanin
albinism
produced by the cumulative effects of UV ray exposure
age spots
what determines the amount of melanin in the skin?
genes
a group of yellowish pigments from food that can also contribute to skin colour
beta-carotene
colour changes also occur as a result in blood flow because of this:
hemoglobin
bluish colour caused by darkening of hemoglobin
cyanosis