Ch. 4.1 - 4.3: Tissue Level Of Organization Flashcards
What are the important characteristics of epithelial tissue?
Cellularity, polarity, attachment, avascularity, regeneration
What are the 4 basic tissue types?
- Epithelial tissue 2. Connective tissue 3. Muscle tissue 4. Neural tissue
Tissues
Collections of specialized cells and cell products that perform a limited number of functions
Epithelial tissue
Covers exposed surfaces, lines internal passageways and chambers, and forms glands
Connective Tissue
- Structural framework for body 2. Transporting fluids and dissolved materials 3. Protects delicate organs 4. Supporting, surrounding, interconnecting other tissues 4. Stores energy reserves 5. Defense
Muscle tissue
Specialized for contraction, includes skeletal muscles, heart muscle, muscular walls of hollow organs
Neural Tissue
Carries information from one part of the body to the other via electrical impulses
Two types if epithelial tissue
Epithelial and glands
Four functions of epithelial tissue
- Physical protection 2. Controls permeability 3. Provides sensation 4. Produce specialized secretions
What three factors maintain integrity of the epithelia?
- Intercellular connections 2. Attachment to basement membrane 3. Regeneration - maintenance and repair
Cell adhesion molecules (CAM)
Transmembrane proteins that bind to each other and to extra cellular material
Hyaluronan, Hyaluronic acid;
An important component of the thin layer of proteogylcans that binds the membranes of adjacent cells
Cell Junctions (3)
Areas of the plasma membrane that attach a cell to another cell or extracellular material. 1. Tight junction 2. Gap junctions 3. Desmosomes
Tight Junction
- Interlocking membrane proteins bind the lipid portions of two plasma membranes. 2. A continuous adhesion belt forms a band inferior to the tight junction, which encircles the cells and binds to neighbors. Bands are attached to microfilaments of the terminal web. 3. TJs prevent prevent passage of water and solutes; isolate lumen from basolateral surfaces
Gap Junction
- Two cells held together by CONNEXONS, interlocking transmembrane proteins. These are channel proteins that form small passageways to transport small molecules/ions. 2. Needed where when tissue activity is coordinated: i.e. beating cilia or heart contractions.
Desmosomes
- Durable interconnections that provide resistance to mechanical stress. 2. CAMs and proteogylcans link opposing plasma membranes 3. Occurs at the ‘dense area’ of cell complex that is connected to the cytoskeleton
Two types of desmosomes
- Spot desmosomes: small discs connected to bands of intermediate filaments. Stabilize the shape of the cell 2. Hemidesmosomes: attaches cell to extracellular filaments in basal membrane. Stabilizes and anchors the position of the cell
Mesothelium
Simple squamous epithelium that lines the ventral body cavities
Endothelium
Simple squamous epithelium that lines inner surface of the heart and all blood vessels
Endocrine glands
Ductless glands. Release their secretions (“hormones”) into the interstitial fluid. Ex: pituitary gland and thyroid
Gland
Collection of epithelial cells that produce secretions
Exocrine Gland
Produce secretions discharged onto the epithelial surface. Most reach surface through tubular ducts Ex: enzymes entering the digestive tract, perspiration on skin, tears in eyes, milk from mammary glands
Modes of exocrine secretion (3)
- Merocrine 2 Apocrine 3. Holocrine
Merocrine Secretion
Released from secretory vesicles by exocytosis. The most common mode of secretion.