Ch. 13: Blood System Flashcards
Define plasma
liquid portion of blood
- contains water, proteins, salts, nutrients, lipids, hormones, vitamins
Define erythrocyte
red blood cell
Define leukocyte
white blood cell
Define thrombocyte
platelet
Define stem cells
unspecialized cell
- gives rise to mature, specialized forms
Define hemoglobin
blood protein containing iron
- carries oxygen in red blood cells
Define bilirubin
orange-yellow pigment in bile
- from the breakdown of hemoglobin when red blood cells are destroyed
Define polymorphonuclear
pertaining to white blood cell with a multilobed nucleus
- neutrophil
Define antibodies
specific protein from lymphocytes in response to bacteria/virus/other antigen
Define antigens
substance that stimulates the production of an antibody
Define albumin
protein in the blood
Define edema
swelling
Define coagulation
blood clotting
Define agglutination
the clumping of blood cells
Define differentiation
What is it also known as?
change in structure and function of a cells as it matures
- specialization
Define hypochromia
pertaining to the reduction of hemoglobin in red blood cells
Define cytology
study of cells
Define erythrocytopenia
deficiency of red blood cells
Define hemolysis
destruction of red blood cells
Define hematocrit
percentage of erythrocytes in a volume of blood
Define hemoglobinopathy
disease of hemoglobin
Define leukocytopenia
deficiency of white blood cells
Define thrombocytopenia
deficiency of platelets in the blood
Define plasmapheresis
removal of plasma from withdrawn blood by centrifuge
Define monoblast
immature monocyte
Define erythrocytosis
increased number of red blood cells than normal in the blood
Define electrophoresis
method of separating serum proteins by electrical charge
Define hematopoiesis
formation of cells
Define hemostasis
stopping the flow of blood
Define blood dyscrasia
disease of the blood
Define anemia
without blood
Name the different types of anemia conditions
- aplastic anemia
- hemolytic anemia
- pernicious anemia
- sickle cell anemia
- thalassemia
Define aplastic anemia
What are the main causes?
failure of blood cell production in the bone marrow
- unknown, idiopathic
- may be linked to benzene exposure or antibiotics
Define hemolytic anemia
What are some examples?
reduction in red blood cells due to excessive destruction
- spherocytic enemia
Define pernicious anemia
lack of mature erythrocytes
- from inability to absorb vitamin B12 into the bloodstream
Define sickle cell anemia
What are some serious complications?
Who’s most at risk?
hereditary disorder of abnormal hemoglobin
- produces sickle shaped erythrocytes and hemolysis
- cells are sticky and can form clumps that reduce or block the flow of blood
- stroke, less blood flow through the lungs
- most common in Africans
Define thalassemia
Where is is most common?
inherited disorder of abnormal hemoglobin production - leads to hypochromia
- Mediterranean/ Asian
Define hemophilia
excessive bleeding
- from hereditary lack of factors for blood clotting
- VIII and IX
Define purpura
multiple pinpoint hemorrhages and accumulation of blood under the skin
Define leukemia
What are some examples?
Why is acute worse than chronic?
increase in cancerous white blood cells
- acute/chronic myeloid leukemia
- acute/chronic lymphoid leukemia
- more fast growing
Define multiple myeloma
malignant neoplasm of bone marrow
- production of antibodies that destroy bone tissue
What can be used to treat leukemia?
- bonemarrow transplant
What are some coagulation tests?
- bleeding time
- coagulation time
- partial thromboplastin time (PTT)
- prothrombin time (PT)
Define bleeding time
time required for blood to stop flowing from a tiny puncture wound
Define coagulation time
time required for venous blood to clot in a test tube
Unabbreviate and define PTT
partial thromboplastin time
- measures other clotting factors
Unabbreviate and define PT
prothrombin time
- test the ability of blood to clot
Unabbreviate CBC
complete blood count
Unabbreviate ESR
erythrocyte sedimentation rate
Unabbreviate Hct
hematocrit
Unabbreviate WBC
white blood cell count
Unabbreviate WBC with diff
white blood cell differential count
Unabbreviate T&C
type and crossmatch
Unabbreviate Hb, Hgb
hemoglobin test
Unabbreviate DIC
disseminated intravascular coagulation
Unabbreviate H&H
hemoglobin and hematocrit
Unabbreviate RBC
red blood cells count