Ch 11 - Other drugs used in dermatologic therapy

Question 1

What are systemic corticosteriods?

Answer 1

used in the treatment of some dermatosis and dermatitis conditions

Question 2

What do systemic corticosteriods do?

Answer 2

affect immunologic and inflammatory activity.

Question 3

The effects of systemic corticosteriods may last from?

Answer 3

a few hours up to several weeks depending on type of steriod

Question 4

What are the clinical uses of systemic corticosteriods?

Answer 4

in the treatment of dermatologic conditions, systemic corticosteroids are indicated for allergic reactions (flea bit etc. ) moist dermatosis, seborrheic dermatitis and acral lick dermatitis

Question 5

What are adverse side effects for systemic corticosteriods?

Answer 5

occur with misuse and long-term use, skin inflammation, pruritus include polyuria, polydipsia, and plyphagia which may result in weight gain

Question 6

What are topical antibacterial agents?

Answer 6

used in the treatment and prevention of superficial bacterial infections of wounds

Question 7

What are topical antifungal agents?

Answer 7

used in the treatment of superficial fungal infections.

effective in the treatment of ringworm and for thrush in equines

Question 8

What are fatty acid supplements?

Answer 8

consist of long chains of carbon atoms with a methyl group -CH at one end

Question 9

Linoleic acid and linolenic acid cannot be synthesized by the ?

Answer 9

dog - must be supplied in the diet

Question 10

Linoleic acid and linolenic acid are called?

Answer 10

essential fatty acids

Question 11

Arachidonic acid is an?

Answer 11

essential fatty acid for cats

Question 12

Fatty acids are responsible for?

Answer 12

the shine of the haircoat and the smooth texture of the skin, can manage itching in a dog or cat

Question 13

Fatty acid supplements are usually derived from?

Answer 13

fish oil or vegetable oil and may be combined with antioxidant vitamins such as A and E

Question 14

What are the clinical uses for fatty acid supplements?

Answer 14

control itching, may improve luster of the skin

Question 15

Adverse side effects of fatty acids are?

Answer 15

vomiting, diarrhea, or increased bleeding times

Question 16

What are counterirritants?

Answer 16

substances that are applied to the skin of horses to produce local irritation and inflammation.

Question 17

counterirritants are sometimes used to ?

Answer 17

treat chronic inflammatory conditions of bone joints, ligaments, tendons, or other tissues below the surface.

Question 18

What is the rationale when using counterirritants?

Answer 18

creating an acute inflammatory condition promotes blood supply to the inflamed area and adjacent tissue. This increased blood supply brings with it more oxygen, white blood cells, antibodies, complement and other factors to promote healing.

Question 19

When counterirritants are applied to the skin, 3 stages or irritant result, they are?

Answer 19

1. rubefaction
2. vesication
3. blistering

Question 20

What is rubefaction?

Answer 20

reddening - indicates mild irritation accompanied by an increase in blood congestion in the skin

Question 21

What is a tightener?

Answer 21

a rubefacient compound, similar to a liniment or a brace that is applied under a cotton leg wrap in an effort to reduce edema around tendons or joints

Question 22

What is a sweat?

Answer 22

contains alcohol and glycerin and is applied under a moisture-proof bandage to reduce edema

Question 23

What are clinical uses for counterirritants?

Answer 23

used for reducing “filling” (edema) around joints or tendons and associated soreness.

Question 24

What are the adverse side effects for counterirritants?

Answer 24

tissue irritation

Question 25

What is vesication?

Answer 25

the second stage of counterirritants - achieved by applying irritating substances under a bandage

Question 26

What are the clinical uses for vesication?

Answer 26

used in the treatment of chronic inflammatory musculoskeletal conditions in horses

Question 27

Adverse side effects for vesication?

Answer 27

severe tissue damage, worsening of the original condition and self-mutilation

Question 28

What are caustics?

Answer 28

substances that destroy tissue at the application site

- used to destroy excessive graulation tissue (proud flesh), superficial tumors (warts) or horn buds.

Question 29

Clinical uses for caustics are?

Answer 29

the control of proud flesh, removal or warts and horn buds in calves

Question 30

Adverse side effects in caustics are?

Answer 30

damage to the adjacent tissue, especially the eye when used on horn buds

Question 31

What are behavior modification drugs in cats and dogs used for?

Answer 31

used in dermatologic conditions

Question 32

Clinical uses for beh. mod drugs?

Answer 32

modify behavior - stop self-licking

Question 33

adverse side effects in beh. mod drugs?

Answer 33

sedation, dry mouth, hypersalivation, vomiting, constipation etc.