Ch 10 Bacterial DNA repair Flashcards

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1
Q

What is mutation?

A

A heritable change in the DNA

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2
Q

What is point mutation?

A

Change in a single base pair

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3
Q

What is transition?

A

Purine>purine
Pyrimidine>pyrimidine

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4
Q

What is transversion?

A

Purine>pyrimidine
Pyrimidine>purine

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5
Q

What is insertion?

A

Adding one or more bases

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6
Q

What is deletion?

A

Subtracting one or more bases

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7
Q

What is inversion?

A

DNA is flipped in orientation

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8
Q

What is reversion?

A

DNA mutates back to original sequence

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9
Q

What is a silent mutation?

A

Does not change the amino acid sequence

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10
Q

What is missense mutation?

A

Changes the amino acid sequence to another

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11
Q

What is nonsense mutation?

A

Changes the amino acid sequence to a stop codon

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12
Q

What is frame-shift mutation?

A

Changes the open reading frame of the gene

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13
Q

What are some mutagens?

A

Chemical agents, Electromagnetic radiation

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14
Q

Electromagnetic radiation: What do x-rays and gamma rays do?

A

Break DNA

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15
Q

Electromagnetic radiation: What do ultraviolet rays do?

A

Form pyrimidine dimers

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16
Q

What is the mutation rate?

A

Number of mutations formed per cell division

17
Q

Mutation frequency?

A

Ratio of mutants per total cells in the population

18
Q

What does the Ames test do?

A

Identifies mutagens

19
Q

What are error-proof pathways?

A

They prevent mutations

20
Q

What are error-prone pathways?

A

Risk introducing mutations when the cell has so much damage it has to mutate or die to survive