Cerebral vasculature Flashcards

1
Q

what % of cardiac output does brain use

A

10-20%

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2
Q

what % of o2 consumption does brain use

A

20%

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3
Q

what % of liver glucose does brain use

A

66%

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4
Q

what are the two sets of vessels supplying brain

A

internal carotid artery - comes through carotid canal

vertebral artery - comes through foramen magnum

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5
Q

what do the two vertebral artery fuse to form

A

basillar artery

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6
Q

what does basillar artery divide into

A

2 posterior cerebral arteries

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7
Q

what is the main branch of the internal carotid artery

A

middle cerebral artery

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8
Q

what is advantage of having circuit of vasculature in brain

A

theoretical chance of flow from other side

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9
Q

how does blood drain from brain

A

from cerebral veins into venous sinuses in dura mater to internal jugular vein

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10
Q

what is the fold of dura that passes down between two hemispheres

A

falx cerebri

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11
Q

what is the name given to the sinus which comes straight down from brain into confluence of sinuses

A

vein of galen

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12
Q

what sinus drains into internal jugular vein

A

sigmoid sinus

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13
Q

what is an intracranial haemorrhage

A

bleeding within cranial cavity

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14
Q

what are the 4 types of intracranial haemorrhage

A

extradural
subdural
subarachnoid
intracerebral

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15
Q

what is an extradural haemorrhage

A

usually due to trauma e.g injury to pterion
immediate clinical affects
can strip dura away from skull - is an arterial bleed and causes high pressure
is a surgical emergency!

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16
Q

what is a subdural haemorrhage

A

can be due to trauma
delayed clinical effects
venous bleed
lower pressure

17
Q

what are subarachnoid haemorrhages

A

found at circle of willis

ruptured aneurysyms

18
Q

what are intracerebral haemorrhages

A

found inside brain

spontaneous hypertensive

19
Q

what is another name for stroke

A

cerebrovascular accident

20
Q

what is the definition of a stroke

A

rapidly developing focal disturbance of brain function of presumed vascular origin and over 24hr duration

21
Q

what % of stroke is caused by thrombo embolic

A

85%

22
Q

what % of stroke is due to haemorrhage

A

15%

23
Q

what is a transient ischaemic attack

A

rapidly developing focal disturbance of brain function of presumed vascular origin and over 24hr duration

24
Q

what is an infarction

A

degenerative changes which occur following occlusion of artery

25
Q

what is cerebral ischaemia

A

lack of sufficient blood supply to nervous tissue resulting in permanent damage if blood flow is not restored quickly

26
Q

what is a thrombosis

A

formation of blood clot

27
Q

what is an embolism

A

plugging of small vessel by material carried from larger vessel
e.h thrombi from heart/atherosclerotic debris

28
Q

what are some signs of stroke

A

impaired speech
face lopsided
cannot raise arms

29
Q

what are the risk factors for stroke

A
age
hypertension
cardiac disease
smoking 
diabetes mellitus
30
Q

what can stroke in anterior cerebral artery cause

A

paralaysis of contralateral structures
leg>face,arm
disturbance of intellect, executive function and judgement (abulia)
loss of appropriate behaviour

31
Q

what can stroke in posterior cerebral artery cause

A

visual deficits
homonymous hemianopia
visual agnosia

32
Q

what can stroke in middle cerebral artery cause

A
= classic stroke symptoms
contralateral hemiplegia arm>leg
contralateral hemisensory deficits
hemianopia
aphasia if left sided lesion