Cerebellar Disorders Flashcards
what makes up the cerebellar cortex?
floccilonodular lobe
vermis and intermediate zone
lateral zone
what makes up the cerebellar nucleus?
fastigial nucleus
interposed nucleus
dentate nucleus
what are the functions of the pontocerebellar?
control voluntary movements
planning/control of precise movements of extremities and distal limbs
timing and initiation of movements in distal limbs
what clinical signs are associated with pontocerebellar?
ataxia or dysmetria
hypermetria
tremors
what neurological deficits are associated with spinocerebellar?
vestibulocerebellar signs
opisthotonus with rostral lobe lesions
head and body turn?
what clinical signs are associated with vestibulocerebellar?
vestibular ataxia
nystagmus usually vertical
head tilt
how common are degenerative disorders?
rare
what is progression like of degenerative disorders?
slow
what degenerates in cerebellar abiotrophy?
mainly purkinje cells: apoptosis
what are the clinical signs of cerebellar abiotrophy?
intension tremor
over reactive head movement, difficulty to portend food
inability to determine space and distance
ataxia
hypermetric gate
abnormal menace reflex
seizures
which horse breeds are affected by cerebellar abiotrophy?
arabians
miniatures
gotland ponies
eriskay ponies
oldenburgs
what do storage disorders lack?
specific enzyme in lysosomes
what is the most vulnerable to storage disease?
cerebellum
all cells affected
when do storage diseases show?
first two years of life
what connects the cerebellum to the brainstem and forebrain?
caudal cerebellar peduncle
middle cerebellar peduncle
rostral cerebellar peduncle
