Case Examples Flashcards
is lymphoma more likely to metastatically spread to the CNS or develop there primarily?
spread there metastatically
what can make a oligodendrocytoma or astrocytoma high-grade?
necrosis
microvascular proliferation
pseudopallisading
mitoses
overt features of malignancy
what is the most common glial tumor?
oligodendroglioma
how many primary CNS tumors are astrocytomas?
20-30%
where are astrocytomas most common?
white matter of cerebral hemispheres
how many primary intracranial tumors in the dog are choroid plexus tumors?
7-10%
where are choroid plexus tumors most common?
4th and lateral ventricles
what do choroid plexus tumors commonly cause?
secondary hydrocephalus
what is feline ischemic encephalopathy associated with?
aberrant migration of Cuterebra fly larvae
who is necrotizing meningoencephalitis most common in?
small breed dogs
what are the gross lesions of necrotizing meningoencephalitis?
asymmetrical, multifocal, bilateral areas of acute encephalitis or foci of malacia, necrosis
collapse of hemispheric gray matter
where are the lesions of necrotizing leukoencephalitis most common?
white matter of cerebral hemispheres
what are the three recognized forms of granulomatous meningoencephalitis?
common disseminated form
disseminated form with angiocentric expansion
focal form
what is equine protozoal myelitis/encephalitis predominantly associated with?
Sarcocystis neurona
what is equine protozoal myelitis/encephalitis associated with?
variably sized areas of necrosis and inflammation throughout the CNS
what usually makes up intravascular lymphoma?
B cells
where does oligodendroglioma have a predisposition for?
frontal, parietal, piriform, temporal lobes
periveentricular location
are astrocytomas usually ill-defined or well-defined?
ill-defined
what are higher grade choroid plexus tumors often accompanied by?
brisk mitotic rate
desmoplasia
what does necrotizing leukoencephalitis typically spare?
meninges
where do lesions from granulomatous meningoencephalitis tend to predominate?
brainstem
cervical spinal cord
where do oligodendromas often arise?
frontal, parietal, piriform, or temporal lobes
peri-ventricular location
what do oligodendromas look like grossly?
well-demarcated
gelatinous, maybe hemorrhage
what do astrocytomas look like grossly?
ill-defined typically
can have hemorrhage
what is the lesion like in feline ischemic encephalopathy?
necrotizing and eosinophil-rich
vasculitis common
what is the etiology of necrotizing meningoencephalitis?
unknown, maybe autoimmune or post-infectious molecular mimicry pattern
